| Background and Objective:Cerebral infarction is one of the most serious diseases that endanger human health.Cerebral infarction had characteristics of high disability,mortality and recurrence rate.The mortality and disability rates are higher than those of early onset,which caused a heavy burden on the the communities and many families.Studies of the recurrence of cerebral infarction are still a hot topic in the medical research.However,there are still some controversies about the determination of risk factors leading to recurrence,the validity of multiple scales for predicting recurrence,the preventive effect of drugs and intracranial and extracranial stents.The purpose of this study is to analyze clinical and imaging differences in patients with or without recurrent cerebral infarction who were hospitalized treated,to find the main risk factors of recurrent cerebral infarction and prediction index,so as to screen out the object who had the tendency of recurrence for strengthening their health education and targeted therapy,thus reducing the recurrence of cerebral infarction.MethodsPatients with the initial onset of acute cerebral infarction who were hospitalized in Neurology Department in our hospital from December 2014 to December 2015 were collected in this study.After the first screening,the corresponding examinations and treatments were performed in accordance with the process,and secondary prevention and treatment were performed routinely after discharged,followed up by telephone or outpatient referral for 1 year,finally,226 patients were screened out for analyzing,who were divided into recurrence group(21 cases)and non-recurrence group(205 cases).SPSS 18 statistical package software was used to analyze the clinical and imaging data of the two groups.Results:(1)21 cases had recurrence among 226 patients within a year,the recurrence rate was about 9.29%.(2)The incidences of hypertension and diabetes in the recurrence group were significantly higher than those in the non-recurrence group,and the differences were statistically significant(P<0.05);there were no significant differences in gender,age,smoking history,BMI,hyperlipidemia and heart disease in both groups(P>0.05).(3)Comparison of M-TOAST type and subtypes between the two groups found that the incidence of atherosclerotic thrombosis(AT type)in the recurrence group(66.67%)was significantly higher than that in the non-recurrence group(43.41%),and the difference was statistically significant(p<0.05).(4)Comparison of the ESSEN score between the two groups and found that the percentage of patients with or above the high risk of ESSEN score in the recurrence group was 71.43%,which was significantly higher than that in the non-recurrence group(34.63%),and the difference was statistically significant(P<0.05).(5)Comparison of imaging data between the two groups:the percentage of unstable plaque in the recurrence group(71.43%)was significantly higher than that in the non-recurrence group(34.15%),the percentage of intracranial or extracranial vascular stenosis in the recurrence group was significantly higher than that in the non-recurrence group,and the difference was statistically significant(P<0.05).Conclusions(1)The recurrence rate of initial cerebral infarction within 1 years was 9.29%in this study.(2)Hypertension and diabetes are the main risk factors of cerebral infarction recurrence.(3)The recurrence rate was significantly higher in patients with unstable cervical plaques or intracranial and extracranial vascular stenosis.(4)The recurrence rate of patients with AT type in M-TOAST was high,and it was consistent with the conclusion that the recurrence rate was significantly higher in patients with unstable cervical plaques or intracranial and extracranial vascular stenosis.(5)ESSEN score can predict the risk of recurrence of cerebral infarction,however,the lack of unstable plaques,intracranial and extracranial vascular stenosis and other imaging data may affect the validity of the prediction. |
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