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Value Of The Essen Stroke Risk Score In Evaluating The Prognosis Of Acute Cerebral Infarction

Posted on:2015-05-31Degree:MasterType:Thesis
Country:ChinaCandidate:S HuFull Text:PDF
GTID:2284330431964980Subject:Neurology
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Objective: Conducted in patients with acute cerebral infarction Essen Stroke RiskScore(ESRS), National Institute of Health stroke scale(NIHSS)and Barthel Index(BI), the aforementioned changes in observational studies and the relationshipbetween indicators discussed ESRS value in prognosis of cerebral infarction.Method: Healthy check-up of80cases were selected for control group and125patients were selected for stroke group, the patients of stroke group satisfied theinclusion criteria and exclusion criteria, and two groups were comparable in age, gendercomposition. All patients were assessed ESRS after admission, stroke group assessedNIHSS score at the time of admission and1week after admission。Stroke patients werefollowed up when discharged,a month, three months,six months,twelve months afterdischarged and assess Bl score. NIHSS score: The first data were marked as “NIHSS1”while the second date were marked as “NIHSS2”, and “NIHSS1subtract NIHSS2” wasmarked as “NIHSS difference”. BI score: discharge (the result is "1"), when dischargeda month (the result as "2"), when discharged three months (the result as "3"), wasdischarged at6months (the result as "4"), at discharge12months (the result as "5"). Alldata were analyzed by SPSS20.0statistics software. the significant level for bilateral test was less than0.05(P<0.05).Results:1. The study included205cases of patients, finally194cases were completed,including75cases of normal group,119cases of stroke group, lost11cases, lost was5.37%.4patients with cerebral infarction recurrence. No patients died.2. Stoke group age score, high blood pressure score, diabetes score, other heartdisease score, smoking score, TIA or ischemic stroke history score, ESRS scores weresignificantly higher than normal group. Previous myocardial infarction score, peripheralarterial disease score slightly higher than normal group, the difference was notsignificant.3.Comparison of ESRS subscales with NIHSS score:65-75years of age group wassignificantly lower than the age <65years group in NIHSS difference(P<0.01), age>75years group was significantly lower than the age <65years group in NIHSSdifference(P<0.01);TIA or ischemic stroke was significantly lower than no history ofTIA or ischemic stroke group in NIHSS2(P <0.05);Comparison of ESRS stratification with NIHSS score:NHISS2was significantlylower than NIHSS1(P<0.01)in stroke group.ESRS0-2group, ESRS≥3groups NHISS2were significantly lower than the NHISS1; ESRS≥3groups NHISS1, NHISSdifference is slightly lower than ESRS0-2group, ESRS≥3groups NHISS2slightlyESRS0-2group, the difference was not significant.Correlation analysis of age,age score,ESRS score and NIHSS score in stroke group:stroke group NHISS1with age, the age score, ESRS score was negatively correlated(P<0.05). NHISS worse with age, age score was negatively correlated (P<0.01), NHISSdifference between ESRS scores no significant correlation. NIHSS2with age, the agescore, ESRS scores were not significantly correlated.4.Comparison of ESRS subscales with BI score:65-75years of age group BI2, BI3,BI4, BI5significantly lower age <65years group (P<0.05,P<0.05, P<0.01, P<0.01); Age>75years group BI2, BI3, BI4, BI5significantly lower age <65years group (P<0.05, P <0.05, P <0.05, P <0.01); hypertension BI1-2, BI1-3, BI1-4was significantlyhigher than non-hypertensive group (P<0.01, P<0.05, P<0.05). Diabetic group BI1, BI2,BI3, BI4, BI5, BI1-3, BI1-4, BI1-5was significantly higher than in non-diabetic group(P <0.01, P <0.01, P <0.01, P <0.05, P <0.05, P <0.05, P <0.01, P <0.01);Comparison of ESRS stratification with BI score: ESRS0-2group BI1-2, BI1-3,BI1-4, BI1-5was significantly lower than the ESRS≥3groups (P <0.01,P<0.01,P<0.01, P <0.05); ESRS0-2group BI1slightly lower than ESRS≥3groups,ESRS0-2group BI2, BI3, BI4, BI5were higher than ESRS≥3groups, the differencewas not statistically significant.Correlation analysis of age,age score,ESRS score and BI score in strokegroup:stroke group age and BI2, BI3, BI4, BI5showed a significant negative correlation(P<0.01, P<0.01, P<0.01, P<0.01), but not with BI1, BI1-2, BI1-3, BI1-4, BI1-5nosignificant correlation; Age score and BI1, BI2, BI4, BI5showed a significant negativecorrelation (P<0.05,P<0.01, P<0.01, P <0.01), but with BI3, BI1-2, BI1-3, BI1-4, BI1-5no significant correlation; ESRS scores and BI1-2, BI1-3, BI1-4, BI1-5was asignificant positive correlation (P<0.01, P<0.01, P<0.01, P<0.05), but with BI1, BI2,BI3, BI4, BI5no significant correlation.Conclusion:1.ESSEN stroke risk score can predict the risk of cerebral infarction, in which age,hypertension, diabetes, other heart disease, smoking, TIA or ischemic stroke sub-scorehistory plays a major role in the forecast.2.ESSEN stroke risk score may reflect the prognosis of patients with cerebral infarction,the higher the score, the worse the prognosis. Among them, age, hypertension, diabetes,smoking, TIA or ischemic stroke in the history of Asian-score plays a major role.
Keywords/Search Tags:Cerebral stroke, ESSEN, NIHSS, Prognosis, Barthel Index
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