Gestational Diabetes And Pregnancy-related Blood Glucose Control Study Of Fetal Malformations

Objetive:(1) To discussion GDM, PGDM correlation with fetal malformations. (2) To discussion GDM, PGDM glycemic control and fetal malformations rele vance.Methods:A retrospective analysis method, based on inclusion and exclusion cr iteria were collected in January 2012-December 2015 in Ningxia Medical Uni versity General Hospital obstetrics pregnancy admitted a total of 308 cases of diabetic mothers. Wherein the GDM group 203 cases, PGDM group 105 cases, select both the same period 4720 cases of maternal normal control group, anal ysis of each group of maternal fetal malformation incidence. According to pati ent blood glucose control during pregnancy, the PGDM and GDM were ivided i nto blood glucose control and blood glucose control are not satisfied with satis faction two subgroups, comparison of the incidence of fetal malformation amo ng the subgroups, To discussion gestational diabetes and blood glucose control during pregnancy and fetal malformation relevance. Data using SPSS17.0 soft ware processing, count data with each group constituting more than representat ion, count data using x2 test, with P<0.05 was considered statistically signific ant.Results:4720 cases of mothers in the control group, the number of 134 cases of fetal malformation, wherein the cardiovascular malformations in 39 cases,1 5 cases of neural tube defects, other malformations,80 cases, cardiovascular d isease and the most common neurological abnormalities. GDM group generatio n number 9 cases of fetal malformation, cardiovascular malformations in 3 cas es, two cases of neural tube defects, Other abnormalities in 4 cases. PGDM nu mber of maternal fetal malformations in 13 cases, cardiovascular malformation s in 6 cases,3 cases of neural tube defects, other abnormalities in 4 cases. The incidence of PGDM group than in the control group and the GDM group were increased, the differences were statistically significant, no significant differen ce GDM group and control group. In terms of cardiovascular disease, PGDM g roup and control group was statistically significant, but between GDM group a nd PGDM, GDM group and control group, the difference was not statistically s ignificant. In terms of neural tube defects, PGDM group and control group was statistically significant, the other two groups was not statistically significant. On glycemic control, PGDM the total incidence of fetal malformations glycemi c control are not satisfied with the control group than in the glucose group incr eased satisfaction, the difference was statistically significant, cardiovascular malformations, neural tube defects and other diseases were not statistically sig nificant. GDM group of patients, the total fetal malformations, neural tube def ects, cardiovascular malformations and other types of malformations was no si gnificant difference in the incidence.Conclusions:1.PGDM cause fetal malformations were significantly increased, it is one of the risk factors of congenital cardiovascular malformations and neu ral tube defects.2.pre-pregnancy diabetes control blood sugar should be active ly satisfaction reserve pregnancy, patients with diabetes have a high risk pregn ancy routine examination, early detection of potential diabetes.3.GDM patient s than in the control group, the incidence of abnormal glucose control in patien ts with GDM group than satisfied dissatisfied groups were not statistically sig nificant, to be on the large sample data and the foundations for further study.