| Diabetes is a growing threat to human health, diabetes prevalence and the number of diabetes patients is growing fast. Given the severe situation of diabetes,taking diabetes as the research object, we set up the deteriorating diabetes early warning system and glycaemic control system of IDDM according to reliability theory and control theory. Then we carry on the research and analysis to the systems.First, we discussed the degradation of diabetes early warning system. With the development of the course of the disease, the system is divided into three states . Based on the characteristic that hyperglycemia can cause irreversible physical injury, we have described the system of partial differential equations.By the state equation of the system can’t find out the steady-state solution, so the Laplace transform method was used to study the patient’s health indices.Results point out that,in the cycle of "uncontrollable-controllable" for blood sugar, finally some body injury can be life-threatening. Eventually, according to the cost function, the cost of treatment are numerically simulated warning that positive life management, such as eat medications on time, pay attention to diet,reasonable exercise, relax, measure blood glucose in time etc.Control blood sugar is the key to the treatment of diabetes. The dosage of insulin directly affects the precision of blood glucose control. So we coupled subcutaneous insulin kinetics and insulin-glucose regulation models as the new dynamics system according to the process from insulin inject to work. From the angle of the orientation control to study the relationship between input and output of the system. Finally a numerical simulation of the program by Matlab verified the rationality of the coupling system and gained the precise input of insulin corresponding to the output target, ensuring blood glucose within the normal range and avoiding the happening of hypoglycemia. |
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