| Objective 1. Through making the analysis of the current situation and the influencing factors of the metabolic syndrome,the one aim of this study was to provides a scientific basis for the prevention of metabolic syndrome of government employee.2.The other aim of this study was to determine the relationship between homocysteine and metabolic syndrome and its components.Methods Selecting a total of 1680 government employee as the research objects who took the physical examination in Tianjin Fourth Central Hospital during the period of January 2014 to December 2015. The measurement datas included height, weight, waist circumference,hip circumference and blood pressure. Homocysteine(Hcy),fasting blood glucose(FPG), total cholesterol(TC), three glycerol ester(TG), high density lipoprotein cholesterol(HDL-C), low density lipoprotein cholesterol(LDL-C) and fasting insulin(FINS) were collected and measured. Filling in the questionnaire about general information,medical history, family history and life habits and so on. According to the diagnostic standard of metabolic syndrome setted by International Diabetes Federation(IDF) in April 2005, the prevalence of MS and its components were explored and influencing factors were analysed.To make further explore the correlation of homocysteine and the metabolic syndrome and its components. Epidata3.1 was using for inputting datas and SPSS17.0 statistical software was using for processing and analyzing.Result 1. The prevalence and age-standardized prevalence of metabolic syndrome about research objects were 22.6% and 19.4%. The prevalence of components of metabolic syndrome: central obesity, hypertension,hypertriglyceridaemia, low HDL-C, high FPG/ diabetes were 48.4%, 46.2%, 24.3%, 0.5%, 30.5%, and the age-standardized prevalence respectively were 46.0%, 40.9%, 23.2%, 0.47%, 26.0%.2.The datas from univariate and multivariate logistic stepwise regression analysis showed that the independent risk factors of MS of the research objects included: age(OR=1.046), low education level(compared with middle school and following, the OR values of the high school /technical secondary school, college, undergraduate, graduate and above respectively were 5.985, 3.370, 3.031, 2.819); divorce or widowed(OR=1.446); snoring(OR=3.187); smoking(OR=1.537);family history of hypertension(OR=1.374). Protective factors included: women(OR=0.704); exercise(OR=0.798); vegetables or fruits(OR=0.746); married(OR=0.110).3. Multivariate stepwise regression analysis showed that age, male, hypertension and BMI were positively correlated with homocysteine, and e GFR was negatively correlated with homocysteine after correcting the influencing factors. Homocysteine wsa one of risk factors for metabolic syndrome [Do not make any correcting the influencing factors, OR=1.024,95% confidence interval(1.012,1.038), P < 0.05]. Homocysteine was an independent risk factors of hypertension [adjusted for age, gender and other factors. OR=1.020,95% confidence interval(1.004,1.036),P<0.05].Conclusion 1?The prevalence of MS for research objects who belong to highly educated groups is lower than the general population. Except for HDL-C, the prevalence of the metabolic syndrome and its components were increased following age, which reached the peak aged 60 to 79 and then declined. The prevalence of metabolic syndrome in male was higher than female between aged from 20 to 59,but the prevalence of metabolic syndrome in male and female was nearly the same after 60 years old.2?Age, low education level, divorced /widowed, snoring,smoking and family history of hypertension were risk factors for metabolic syndrome.And the protective factors included exercise, vegetables / fruits, female and married.3?Homocysteine was not an independent risk factor for metabolic syndrome, which may be associated with metabolic syndrome through making the impact on the hypertension. |
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