A Cross Sectional Study On Prevalence And Risk Factors Of Metabolic Syndrome In Yunnan Province,2010

ObjectivesWe conducted this study to clarify the prevalence of metabolic syndrome (MS) in Yunnan province, and to explore the risk factors and high risk population of suffering from MS. The interventions based on the finding of this study were developed for the practice of MS control on individual level and community level.MethodsWith multistage stratified cluster random sampling method,3600permanent residents above the age of18years were selected for across-sectional study including questionnaire survey, physical examination and laboratory test. The definition of Metabolic syndrome (MS) was following the Joint Committee for Developing Chinese Guidelines on Prevention and Treatment of Dyslipdemia in Adults,2007. The prevalence was standardized according to the distribution of age and sex among the population of China,2000. According to the characters of the variables, the data was described using percentage, mean, median, et al. Comparative analysis were performed by t test for means, Chi-squier test for rates, Wilcoxon test for the variables under abnormal distribution. Multiple logistic regression was used to estimate the association between the risk factors and MS attack.ResultsBased on the JCDCG criteria, there were568MS patients among the study population. The prevalence (standardized prevalence) of MS was15.8%(14.8%),17.5%(17.0%) in the males and14.2(13.0%) in the females (P=0.007). Aged of18-44years,45-59years,60years, the prevalence were11.2%,23.0%,21.7%, respectively.16.0%,23.2%,13.2%in males, and6.8%,22.9%,29.6%in females. The prevalence of middle aged and the aged was similar, higher than youth class (P<0.001). In male, MS patients were younger. In females, prevalence of MS increased with age (χ2trend=126.14, P<0.001). Prevalence of man’s youth class was higher than women (16.8%vs6.8%,P<0.001) and the old aged females than males have higher rate (31.0%vs12.6%, P<0.001).20.7%prevalence in urban residents and14.0%in rural residents (P<0.001). The prevalence of Han was higher than national minority (18.8%vs11.3%, P<0.001). The prevalence of office workers was23.8%. Different cultural levels of male residents, MS prevalence increased with increasing education level (χ2trend=8.34, P=0.004); Women, by contrast, its prevalence decreased with increasing education level (χ2trend=17.65, P<0.001).The detection rate of lower HDL-C, abnormal blood pressure, high TG, abnormal fasting plasma glucose, and central obesity were34.4%,29.3%,28.7%,18.3%and14.4%, respectively. The main metabolic disorder combination of MS was lower HDL-C+high TG+abnormal blood pressure. There was67.7%metabolic disorder combination of the respondents.Result from the multiple logistic regression showed that age (middle aged vs youth class, OR=2.643,95%CI:1.998～3.496; the aged vs youth class, OR=3.452,95%CI:2.327～5.122), ethnic (OR=0.658,95%CI:0.502～0.862), smoking (OR=1.686,95%CI:1.252～2.271), excessive alcohol consumption (OR=1.960,95%CI:1.229～3.124), family history of hypertension (OR=1.450,95%CI:1.073～1.958), family history of diabetes (OR=2.045,95%CI:1.145～3.653), BMI(over weight vs normal weight, OR=5.113,95%CI:3.844～6.802; obesity vs normal weight, OR=15.289,95%CI:10.461～22.346),IR(OR=3.978,95%CI:3.038～5.208), the intake frequancy of meat and eggs (OR=1.340,95%CI:1.087～1.651; OR=0.797,95%CI:0.651-0.975) were significantly associated with MS. ConclusionAccording to the results of this study, middle aged and the aged of men, older women, Han nationality, smokers, excessive alcohol consumption, family history of hypertension, family history of diabetes, overweight, obesity, IR, more meat eating are high risk population. Depending on the prevalence of gender characteristics and modifiable risk factors, we should adopt comprehensive prevention and control measures to reduce CVD, T2DM and other MS-related chronic diseases caused by the loss of health.