| Objective To investigate the bacterial distribution and antibiotic resistant in intensive care unit(ICU) of hospital infection and to provide evidence for clinicians to appropriately choose antibiotics.Methods The pathogen features and resistance for drug of ICU patients specimens with hospital infection were taken for statistical analysis from 2011 to 2013.Results Totally 1270 non-repetitive strains were isolated, in which 895(70.47%) were G- strains and 375(29.53%) were G+stains. Acinetobacter baumannii accounted the most part of the G- strains, then were the klebsiella pneumoniae, Escherichia, pseudomonas aeruginosa. Among G+ stains, The most G+ stains was Staphylococcus aureus, and nest were Enterococcus faecalis and Staphylococcus epidermidis. Klebsiella pneumoniae and Escherichia showed increasing resistance to both the third and fourth generations of Cephalosporins but relatively high sensitivities to meropenem and amikacin while the rate of resistance didn't exceed 20%. The drug resistance of pseudomonas aeruginosa to the third and fourth generation of Cephalosporin and carbapenems presented the downward trend, while the resistance to levofoxacin and ciprofloxacin increased year by year, and the resistance rate were more than 65% by 2013. The resistance rates of Acinetobacter Baumannii to combination of Piperacillin Sodium and Tazobactam Sodium, to the third and forth generations of Cephalosporins as well as Imipenem showed increasing tendency, especially the resistance rate to Imipenem, which has already exceeded 70% in 2013. The drug resistance rate of Staphylococcus Aureus and Enterococcus faecalis to Erythromycin, clindamycin and Fluoroquinolone Antibiotics all showed an increasing tendency.Conclusions The drug-resistant bacteria were the main pathogens of ICU patients specimens with hospital infection, and more attention should be paid to the monitoring of its drug resistance and infection treatment. |
PDF Full Text Request