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Evaluation Of Correlations Between Glycemic Variability And Aging Type 2 Diabetes With Community Acquired Pneumonia

Posted on:2017-06-14Degree:MasterType:Thesis
Country:ChinaCandidate:N XinFull Text:PDF
GTID:2334330503973946Subject:Internal Medicine
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Objective: To evaluate the correlations between glycemic variability and aging community acquired pneumonia(CAP) in Type 2 diabetes,including community acquired pneumonia on the impact of glycemic variability and glycemic variability on the impact of severity of CAPMethods: 131 cases of elderly type 2 diabetic patients' SDBG were collected(including76 cases of male 55 cases of female, 68 cases of patients with CAP, not complicated with infection in 63 cases) during June 2015 to December 2015 in the First Affiliated Hospital of Fujian Medical University. According to the distribution of the group,they were divided into two groups(SDBG?3.95 and SDBG>3.95). Compared physiological indicators including sex,the number of cap, insulin therapy, complications of diabetes, cholesterol, course of disease, age and Hb A1 C. Data were analyzed by using logistic regression method.For patients with CAP,they were divided into two groups(PSI?90 and PSI>90). Compared physiological indicators including SDBG, lage, blood glucose, age, diabetic duration,Hb A1 C,sex, differences in frequency of hypoglycemia and other indicators.Data were analyzed by using logistic regression method.Results:(1) Compared to the SDBG?3.95 group, the patients with SDBG>3.95 exhibited increasing number of people with CAP,triglycerides, creatinin,Hb A1 C,LDL and lower frequency of intensive insulin treatment(P<0.05).(2)Logistic regression analysis: Hb A1C(OR:1.448,95%C.I.:1.119-1.873),CAP(OR:2.516,95%C.I.:1.096-5.773),LDL(OR:1.851,95%C.I.:1.223-2.801),creatinine(OR:1.007,95%C.I. : 1.000-1.015), intensive insulin treatment( OR : 0.389, 95%C.I. :0.173-0.875)(3)Compared to the PSI?90 group, the patients with PSI>90 exhibited ncreasing number of SDBG,LAGE,Hb A1 C and female( P < 0.01).(4)Logistic regression analysis: Hb A1C(OR:1.490,95%C.I.:0.994-2.232)?SDBG(OR:1.771,95%C.I.:1.132-2.772)male(OR:0.236,95%C.I.:0.059-0.936)Conclusion: Type 2 diabetic patients(Hb A1C>7.5%) with CAP have more glycemic variability than those without infection. For the patients with poor glycemic control, blood glucose fluctuation is related to the severity of diabetes. For the patients with poor glycemic control, blood glucose fluctuation can be a supplement to the PSI score with CAP patients in type 2 diabetes,which could assess the severity of the infection.
Keywords/Search Tags:glycemic variability, Type 2 diabetes, community acquired pneumonia
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