Relationship Between Platelet To Lymphocyte Ratio And Type 2 Diabetes Mellitus With Community Acquired Pneumonia,and Evaluation Of Diagnostic Value

Objective: By analyzing the clinical characteristics of the platelet to lymphocyte ratio in type 2 diabetic patients with community-acquired pneumonia,to explore the correlation between them,and to evaluate the value of the platelet to lymphocyte ratio in the diagnosis of type 2 diabetic patients with community-acquired pneumonia.Methods: From September 2018 to September 2019,400 patients with type 2 diabetes who were hospitalized in the Fourth Affiliated Hospital of China Medical University were selected and 67 healthy people who had physical examination in the physical examination center were collected at the same time.According to whether they were combined with community-acquired pneumonia,they were divided into three groups: 200 patients with type 2 diabetes and community-acquired pneumonia,200 patients with type 2 diabetes excluded from community-acquired pneumonia and 67 healthy people.The clinical data and biochemical examination were collected and analyzed by SPSS 24.0.Result:1.Compared with the group of type 2 diabetes without community-acquired pneumonia infection,there were statistically significant differences in age,insulin-adopted rate,glycosylated hemoglobin,high-sensitivity c-reactive protein,erythrocyte sedimentation rate,triglyceride,total cholesterol,lactate dehydrogenase,carbohydrate antigen 125,thyroid-stimulating hormone and uric acid in the group of type 2 diabetes with community-acquired pneumonia(p < 0.05).There were significant differences in white cell count,lymphocyte count,neutrophil count,neutrophil ratio and PLR in three groups.PLR was the highest in type 2 diabetes mellitus with community acquired pneumonia(p< 0.05).2.PLR was positively correlated with age,history of diabetes mellitus,glycosylated hemoglobin,white cell count,neutrophil count,neutrophils ratio,platelet count,high-sensitivity c-reactive protein,erythrocyte sedimentation rate and carbohydrate antigen125(p <0.05).It was negatively correlated with diastolic pressure,lymphocyte count,uric acid,thyroid-stimulating hormone and free triiodothyronine(p < 0.05).There was no correlation with fasting blood glucose,blood pressure and body mass index(p > 0.05).3.PLR,age,glycosylated hemoglobin,triglyceride,erythrocyte sedimentation rate and high-sensitivity c-reactive protein were the risk factors of community-acquired pneumonia in type 2 diabetic patients(p< 0.05).Lymphocyte count was the protective factor of type 2 diabetes mellitus with community acquired pneumonia(p < 0.05).4.According to the analysis of the receiver operator characteristic curve,PLR can be used as a diagnostic index for type 2 diabetic patients with or without community-acquired pneumonia.The best estimated critical value is 144.67.The diagnostic sensitivity is 56.4%,the specificity is 88%,the area under the curve is 0.701,the 95% CI is 0.624-0.732,p = 0.000.Conclusion: The platelet to lymphocyte ratio is closely related to type 2 diabetes mellitus complicated with community acquired pneumonia,the platelet to lymphocyte ratio increased in patients with type 2 diabetes mellitus and community acquired pneumonia and can be used as an auxiliary diagnostic index in the prevention and treatment of type 2 diabetes mellitus complicated with community acquired pneumonia.