| Purpose of research: Through the clinical observation of sheng mai yang xin ke li, Discuss Sheng mai yang xin ke li of qi and Yin deficiency in patients with chronic heart failure(CHF) clinical symptoms, laboratory results(immune inflammatory indexes), Sheng mai yang xin ke li in qi and Yin deficiency type in patients with chronic heart failure using the efficacy and safety.The research methods:To 50 cases of qi and Yin deficiency in patients with CHF,25 cases were randomly divided into test group and control group in 25 cases. The control group given conventional treatment of western medicine alone,Experimental group on the basis of conventional treatment of western medicine combined with pulse yang xin granule.Two groups of 6 weeks after treatment respectively. Observe two groups before and after treatment: The doctor of traditional Chinese medicine syndrome and comprehensive curative effect?Minnesota life quality score?Echocardiographic index(left ventricular ejection fraction)?Cardiac function classification(NHYA hierarchical)?BNP?Immune inflammatory indicators(Interleukin – 6?Tumor necrosis factor alpha?Endothelin- 1)changes of the indicators.The results of the study:1 ? Experimental group and control group before and after treatment of TCM symptoms were significantly improved(P < 0.01),Two groups of Chinese comprehensive treatment the total effective rate was 96%,Two groups of comprehensive effect of nonparametric test, there was a significant statistical significance(P < 0.01),Experimental group was better than the control group.2?Two groups of life quality score for statistical analysis,Experimental group and control group were significantly improve patients' quality of life(P < 0.01), The experimental group was better than control group(P < 0.01).3?sheng mai yang xin ke li: Experimental group and control group on the influence of left ventricular ejection fraction statistical results were P = < 0.01, Shows the two groups in improving treatment in patients with left ventricular ejection fraction aspect have the obvious curative effect, Experimental group and control group curative effect on improvement of left ventricular ejection fraction was statistically difference, And the experimental group is better than that of control group(P < 0.05).4?The effects of heart to heart function classification(NHYA):Compare the two groups before treatment group(P > 0.05), and after treatment comparison between groups were no statistical difference(P > 0.05).5?The two groups in terms of lower BNP in patients with chronic heart failure treatment has obvious curative effect(P = 0.01),Experimental group compared with control group curative effect,Statistically significant in terms of reducing the BNP,And the experimental group is better than that of control group(P < 0.05)6?nalysis of the statistics in two way are P < 0.01 significant statistical significance,Statistical analysis between the two way P < 0.05(tumor necrosis factor alpha P = 0.045, interleukin- 6 P = 0.031, endothelin- 1(P = 0.038) were statistically significant,To show that the experimental group to improve heart failure in patients with immune inflammatory is better than that in control group.Research conclusions:The test results showed,Experimental group and control group can obviously improve the curative effect of chronic heart failure patients,But patients can further reduce symptoms and signs,To improve exercise tolerance and quality of life,That add sheng mai yang xin particles on the basis of western medicine treatment of diastolic heart failure the curative effect is superior to pure western medicine treatment, That use sheng mai yang xin ke li particles combined western medicine treatment of chronic heart failure is safe and effective. Sheng mai yang xin ke li is worth clinical reference and promotion. |
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