The Clinical Research Of Chinese Traditional Medicine Combined With Ginger Moxibustion Intervention In Obesity With IGR

Objective:To observe the clinical effect of Herbal Oral Administration(Jianpitiaoganyin) with the ginger moxibustion intervention in obesity complicated with impaired glucose regulation(IGR).Method:Subjects who meet the requirements of the study were randomly divided into treatment group(30 cases) and control group(30cases)by a randomized and controlled clinical trial,the Two groups were included in the basic treatment of diet controlling and regular exercise. On this basis, the subjects in the treatment group ought take the decoction of Jianpitiaoganyin and do the ginger partitioned moxibustion;On the same basis, subjects in the control group treatment with metformin, the observation period was 12 weeks.And analysis the test data with SPSS17 software,Observing the Change of TCM clinical syndrome integral evaluation of the two groups and the obesity related indicators(body weight, waist circumference, BMI, WHR), detection of glucose and lipid metabolism(TC?TG?HDL-C?LDL-C?FPG?2h-PG?FINS?HOMA-IR?Hb A1c).Result:Before and after treatment,the obesity related indicatorsof the two groups(body weight, BMI, WC, WHR) were all decreased,But the treatment group's weight, BMI, waist circumference decreased more significantly, the two groups after treatment, body weight, BMI,WC difference was statistically significant(P<0.01),The difference of WHR between the two groups was statistically significant(P<0.05),two groups of TCM clinical symptom scores were significantly reduced(P<0.01), the treatment group decreased significantly than that in control group;In the aspect of improving lipid metabolism, The decline of TC, TG, LDL-C, and the rise of HDL-C in the treatment group were significantly with statistical significance(P<0.05);The control group TC, TG, LDL-C decreased with statistical significance(P<0.05), the change of HDL-C was not statistically significant(P>0.05);In the improvement of glucose metabolism, there was statistical significance in two groups after the treatment, 2h-PG, FINS, Hb A1(P<0.01), the difference was statistically significant difference(HOMA-IR P<0.05),In the treatment group, 2h-PG, FINS, HOMA-IR, Hb A1 decreased significantly,and have a same effect with metformin in the regulation of FPG.Conclusion:The therapy of Jianpitiaoganyin with the ginger moxibustion can effectively reduce the patientsofwith obesity and IGR s' weight, BMI, waist circumference, WHR obesity related indexes, reduce obesity, decrease TC? TG, regulate their glucose and lipid metabolism, improve insulin resistance; in traditional Chinese medicine syndromes, this therapy can effectively improve the clinical symptoms of patients with obesity and IGR, curative effect is remarkable.The total efficacy of the treatment group was significantly better than that of the control group,And the total effective rate of the treatment group was significantly higher than that of the control group.