Clinical Research For Self-drafted Prescription Of BuShen YiSui (Tonifying Kidney And Marrow) For Treatment Of Knee Osteoarthritis (Liver And Kindey Deficiency Type)

Purpose: Aim to observe the clinical efficiency in clinical research for self-drafted prescription of Bu Shen Yi Sui(tonifying kidney and marrow)for treatment of knee osteoarthritis(Liver and Kidney Deficiency Type,providing references for clinical research for treatment of knee osteoarthritis.Method: This paper follows random parallel control study methods,selecting 120 patients with KOA diagnostic criteria of traditional Chinese and Western medicine from ChangChun University of Chinese Medicine affiliated hospital orthopaedic outpatients and inpatients from January 2015 to December.Patients were randomly divided into treatment group and control group,60 cases in each group.Oral drug for control group is Jin Wu Gu Tong capsule.Conditions of two groups are the same: gender,age,course of the disease,conditions of the disease etc.there is no significant difference(P > 0.05).Control group: oral medications of Jin Wu Gu Tong capsule.Taking method is 1.5 g each time orally,3 times a day,take with warm boiled water,for one month.Treatment group: decoct and take 150 ml of self-drafted prescription of Bu Shen Yi Sui(tonifying kidney and marrow),morning and evening,for one month.Two visits are scheduled across the whole process of the project.The first visit was(treatment day 1)when parents entered the group.According to entry time,respective sequence number were assigned to patients.The second visit was arranged at the end of treatment.The degree of improvement of patients’ clinical symptoms are then respectively evaluated,in order to evaluate drug safety and effectiveness.Result: According to the results of the treatment of patients in the two groups,in control group,4 patients were cured;28 showed excellent response;22 responded well and a total of 6 patients did not respond to the treatment,and the total efficacy rate is 90.0%.In treatment group,6 patients were cured;25 showed excellent response;25 responded well and a total of 4 patients did not respond to the treatment,and the total efficacy rate is 93.3%.According to statistics analysis,The treatment group has demonstrated equivalent overall efficacy as the control group.but the treatment group has shown better results than the control group in the improvement in pain.Conclusion: The treatment group has demonstrated equivalent overall efficacy as the control group.but the treatment group has shown better results than the control group in the improvement in pain,which is worthy of clinical promotion.