Survey And Analysis Of Nutritional Status Prior To Interventional Treatment In Liver Carcinoma Patients With PG-SGA

Objective:Application Patient-Generated Subjective Global Assessment(PG-SGA)form,conduct survey for patients of hepatocellular carcinoma who prior to interventional treatment,to investigate the nutritional status for this people and to analyze the clinical significance.Materials and methods:1.303 cases of hepatocellular carcinoma patients in the second affiliated hospital of dalian medical university,who prior to interventional treatment in September 2014 to March 2015 were investigated.2.Using the PG-SGA to investigate the nutritional status for this people by professionals inquired about patients' nutrition support situations and activities before admitted to hospital,and related physical examination and laboratory tests(blood routine,APTT?PT-T,liver biochemistry,etc.)was performed Within 48 hours?3.Collect information and entry of excel software,according to the PG-SGA qua litative nutritional evaluation results for grouping patients,using SPSS17.0 software for different grouping patients' sex,age,stage and grade of the CHILD,BMI,blood routine,blood clotting,blood sugar,liver biochemistry for statistical analysis.Results:1.In 303 patients who prior to interventional treatment of liver cancer well-nourished accounted for only 16.8% of patients,a total of 51 cases.The remaining 83.2% of patients have different degree of malnutrition,severe malnutrition,be badly in need of nutritional support treatment,108 cases of patients,accounting for 35.6%.2.In 303 patients who prior to interventional treatment of liver cancer Male 249 cases,accounting for 82.2%,female 54 cases,accounting for 17.8%.Gender has no statistical significance with PG-SGA degree distribution(P > 0.05).3.In 303 patients who prior to interventional treatment of liver cancer CHILD A class patient 162 cases,accounting for 53.5%,CHILD class B patient 141 examples,accounts for 46.5%.CHILD grade has no statistical significance with PG-SGA degree distribution(P > 0.05).4.In 303 patients who prior to interventional treatment of liver cancer with BCLC A period(7.9%);B patients(56.4%);C,35.6%.18 cases(75%)in A period of patients with malnutrition,no severe malnutrition.132 cases of malnutrition(77.2%)in B period of patients with malnutrition,51 patients(29.8%)with severe malnutrition.102 cases(94.4%)of malnutrition in C period of patients,57 patients(52.8%)with severe malnutrition.Comparison of BCLC staging in the different PG-SGA degree distribution was statistically significant(P = 0.016).5.303 cases of prior to interventional treatment for Hepatocellular carcinoma patients' age,BCLC staging,PLT,AST,DB showed a positive correlation with PG-SGA degree;BMI,HB,A/G,ALB,PA showed a negative correlation with PG-SGA degree;and the CHILD classification,LYM,PT,APTT,ALT,TB are not related.BMI,A/G : well-nourished group(PG-SGA degree A)and malnut rition group(PG-SGA degree B + C)compare the difference was statistically significant(P < 0.05),mild-to-moderate malnut rition group(PG-SGA degree B)and severe malnut rition group(PG-SGA degree C)has no statistically significant difference(P > 0.05);HB,PLT,AST,ALB,PA: C and A + B the difference was statistically significant(P < 0.05),A and B there was no statistically significant difference(P > 0.05).Age,DB: A and C difference was statistically significant(P < 0.05).Conclusion:1.The malnutrition rate before interventional therapy of liver cancer patients is higher,and nutrition screening assessment should be implemented for every patients.2.Before interventional treatment of liver cancer patients' age,BCLC staging,PLT,AST,DB showed a positive correlation with;BMI,HB,A/G,ALB,PA showed a negative correlation with nutritional status.3.Before interventional treatment of liver cancer patients' PG-SGA score had significant correlation with BMI,liver function,BCLC staging,It is a suitable nutrition assessment method for received interventional treatment of liver cancer patients.