The Relationship Between Recurrent Respiratory Tract Infections And Vitamin A And E Levels In Children

Objective:Through detection of recurrent respiratory tract infections,respiratory infections and healthy children the levels of serum vitamin A,E,to explore vitamin A,E and the development of the relationship between recurrent respiratory tract infections in,vitamin A,E synergy adjuvant therapy for clinical provides the theory basis for recurrent respiratory tract infections.Methods:Selection from June 2015 to March 2016 during the Fist Affiliated Hospital of Dalian Medical University and Dalian Shengjing Hospital,China Medical University Hospital outpatient service and a total of 179 cases of hospitalized children,including children’s recurrent respiratory tract infections 69 cases,in general,a total of 60 cases of respiratory tract infection children,at the same time to hospital check-up normal children of outpatient service medical healthy children(control group),50 cases,at the same time to collect general information(gender,age,weight,etc.),and follow-up of 69 children with recurrent respiratory tract infections,2 weeks after the outpatient care.By high performance liquid chromatography determination of vitamin A and E level in serum.Data using SPSS20.0 statistical software for statistical analysis.Gender make comparisons between groups by chisquare test(?2),the measurement data after normal analysis with the mean + /-standard deviation(x ± s)form the comparison,mean comparison between groups using single factor analysis of variance(One-Way ANOVA),t test,two factors inspection using Pearson correlation,P < 0.05 for the difference is statistically significant.Results:1.Recurrent respiratory tract infections group,general respiratory infection group,control group in three groups in gender composition(? 2=1.071),there was no statistically significant difference(P>0.05);Three groups of children’s average age is(4.86 ± 2.84),(5.26 ± 3.42),(4.75 ± 3.60)years old,there was no statistically significant difference by comparison(P>0.05);Three groups of children the average weight is(18.89 ± 7.43)kg,(21.06 ± 10.31)kg,(19.27±10.79)kg,there was no statistically significant difference by comparison(P>0.05).2.Three groups serum levels of vitamin A and vitamin E:recurrent respiratory tract infections,general respiratory infection group,control group vitamin A levels is(0.21±0.08)mg/L,(0.26 ± 0.11)mg/L,(0.36 ± 0.08)mg/L.Recurrent respiratory tract infections,general respiratory infection group,control group vitamin E levels is(6.16±1.65)mg/L,(6.86 ± 1.36)mg/L,(7.59 ± 1.92)mg/L.Recurrent respiratory tract infections and respiratory infections commonly group the levels of serum vitamin A and E were significantly lower than normal children,statistically significant difference(P<0.05);Repeated respiratory infection group the levels of serum vitamin A,E is lower than the general respiratory infection group,difference has statistical significance(P<0.05).3.The comparison of serum levels of vitamin A and E in children with recurrent respiratory tract infection of different ages and gender: Vitamin A level of children in different age groups of recurrent respiratory tract infection comparison shows that young children group(1~3 years old),preschool group(3~6 years old),school age group(>6years)vitamin A levels respectively(0.25±0.08)mg/L,(0.20±0.07)mg/L,(0.19±0.07)mg/L,suggesting that with the increase of age,children’s vitamin A levels showed a downward trend,the difference is statistically significant(P<0.05).Different age groups of children recurrent respiratory tract infections vitamin E level comparison shows:preschool group(1~3 years old),group(3~6 years old)of preschool and school age group(>6 years old)vitamin E level respectively(6.68±1.78 mg/L),(6.19±1.51mg/L),(5.67±1.59 mg/L),there was no statistically significant difference(P>0.05).Different age group sex vitamin A,E,horizontal comparison,there were no statistically significant difference(P > 0.05).4.The comparison of serum vitamin A and E level in active period and stable period of recurrent respiratory tract infections children showed that the level of vitamin A in active period and stable period respectively(0.21±0.07)mg/L,(0.29±0.06)mg/L,vitamin A level in active period is below the level of vitamin A in stable period,the difference was statistically significant(P<0.05);level of vitamin E in active period and stable period respectively were(6.16±1.65)mg/L,(7.47±1.80)mg/L,vitamin E level in active period below the level of vitamin A in stable period with statistically significance(P<0.05).5.The correlation between Serum vitamin A level and vitamin E level:repeated respiratory tract infections group,the serum vitamin A level and vitamin E level correlated significantly and positively,with statistical significance(r=0.565,P<0.05).Conclusions:1.Children with recurrent respiratory tract infections serum levels of vitamin A,E is related to the occurrence and development of vitamin A and E levels might be the risk factor of recurrent respiratory tract infections in children.2.Repeated respiratory infection of children activity below the stability level serum levels of vitamin A,E,early intervention for vitamins A,E,the recovery of recurrent respiratory tract infections may play A positive role.3.Repeated respiratory infection of children is related to serum levels of vitamin A and vitamin E,vitamin A and vitamin E can be combined to help children repeated respiratory infection prevention and control.