The Clinical Observation Of Modified Changpu Yujin Decoction In The Treatment Of Sleep Disorder After Stroke(Obsessed With Phlegm Turbidity Resistance Syndrome)

ObjectivesIn this study,post-stroke sleep disorder(phlegm orifices type)were enrolled through systematic observation Iris turmeric flavored soup treatment of the disease clinical efficacy and safety,as Iris turmeric flavored soup is widely used to provide a reliable basis.Methods1.After collecting 61 cases from March 2014 to October 2015 in Hubei University of Chinese Medicine subsidiary of Wuhan City Chinese Medicine Hospital Encephalopathy stroke of sleep disorders,TCM is phlegm type orifices.Eligible patients will be randomly divided into two groups according to treatment,the treatment group of 35 patients in the control group of 26 patients.2.Treatment: The two groups are the conventional method of preventing stroke recurrence.Control group was treated Shu Mian capsules,each three,respectively,after dinner or before bedtime and twice orally.Daily oral treatment group self Iris turmeric flavored soup(Fu Shen 10 g,Polygalaceae 15 g,Shichangpu 15 g,turmeric 15 g,Coptis 6g,cinnamon 2g,Bozi 10 g,Chuanxiong 6g,earthworm 6g),each 200 ml,points afternoon and before going to bed two hours twice a day orally.Both groups were assessed for efficacy after 45 days.3.Observation and treatment and control groups before and after treatment changes in the overall efficacy of sleep,sleep quality changes,neurologic impairment degree of change,and change syndromes occurred during treatment discomfort.For the treatment and control groups were evaluated total efficiency,accurate records PSQI score,neurological deficit scores,Epworth scale score,TCM symptoms scale score,and adverse drug reactions,to Iris turmeric flavored soup after stroke the effect of sleep disorders make detailed and accurate assessment.4.Before treatment and at the end of the recording general physical examination,urine stool,electrocardiogram,a full set of biochemical,coagulation,safety observation.And the emergence of the process of observation and recording of medication side effects,tolerability after exploring Iris turmeric flavored Treated stroke and sleep disorders security.5.Using SPSS17.0 software for data analysis,measurement data using t test,count data using ?2 test.P<0.05 considered statistically significant difference,P<0.01 considered statistically significant difference.Result1.Two groups of patients in terms of age,sex,duration of basic information on statistical analysis,no significant difference;and neurologic impairment before treatment,PSQI,Epworth scale,traditional Chinese medicine syndrome,the no significant difference,indicating that the two groups mainly due to fluctuations in the patient's condition changes have unity.2.The overall effect of the two groups of patients with sleep quality,sleep disorders and improve the efficacy of traditional Chinese medicine syndromes are sure,but Iris turmeric flavored soup group more significant than the effect of Shu Mian capsule group.3.Neurological deficit scores before and after treatment,TCM syndrome score compared two groups has declined,and there were significant differences;compare the two groups after the treatment group score decreased significantly compared with the control group significantly,showing that compared with the control group,treatment group has more advantages,iris turmeric soup flavored show more improvement in patients with neurologic impairment and clinical symptoms,ie,symptoms associated with improvement more advantages.4.After treatment,PSQI score somewhat lower than than before,indicating that the two drugs could improve sleep quality;the treatment group scores decreased obviously,showing Iris turmeric flavored soup in improving sleep quality more advantages.In each factor in improving the quality of sleep,compared two groups of scores before and after treatment were decreased,but the treatment group was significantly higher degree of decline seen Iris turmeric flavored soup is better than Shu Mian capsule.5.After treatment Epworth scale score in the control group had no significant changes in the treatment group Epworth scale score decreased significantly,indicating Iris turmeric flavored soup can improve the degree of daytime sleepiness in patients with sleep and Shu capsule is not obvious.6.Two groups of patients before and after treatment,general physical examination,ECG and all laboratory tests to check no obvious abnormalities and changes visible iris turmeric flavored soup of safety and reliability.ConclusionIn short,Iris turmeric flavored soup after stroke clinical efficacy of the treatment of sleep disorders(phlegm orifices type)a significant positive effect and can effectively improve nocturnal sleep and daytime sleepiness,insomnia and sleepiness have two-way adjustment,and promote neurological restoration and improvement of clinical symptoms and function.And in the process of taking does not appear obvious side effects.