| Objective:Improve the quality evaluation system of polygonum multiflorum thunb; Study the main factors that affect traditional process of polygonum, established the best process technology by orthogonal; Study fresh-cut process parameters of polygonum pieces, it is preferable to optimum the best processing of fresh processing by orthogonal experiment; By Comparing traditional origin processing techniques with fresh process techniques, preferably a processing technology that suitable large-scale production requirements and processing of the origin of the integration, to ensure the quality stable and controllable of polygonum pieces. The draft prepared that about origin processing processing integration process specification of polygonum, standardized polygonum origin processing industrial production processing technology, to provide a stable and feasible, controllable parameters of the production process of polygonum industrial production.Methods:1. Determination stilbene glucoside and anthraquinone combine content of polygonum by HPLC;Determination polysaccharide content of polygonum by UV spectrophotometry; Integrated traditional appearance and alcohol-soluble extract to evaluate quality Polygonum Pieces.2. On the basic of analysis the current situation of traditional processing and fresh processing about Polygonum, select the immersion time, moistening time, when the water content of the slice, slice thickness, drying temperature as parameters,optimum traditional processing and fresh processing of Polygonum by orthogonal experiment of L(9)34.3. compared with the two processing use time and the pieces by processing related chemical composition level of content, to further explore the feasibility and advantages of industrial processing about polygonum,combined with the actual production,explore the industrial production technology about polygonum.Result:1. On the basis of the determination to the pharmacopoeia item stilbene glucoside and anthraquinone binding on the increase in alcohol-soluble extract having antioxidant activity of polysaccharides and Shouwu Prepared under the comprehensive evaluation more reasonable,can control the quality of polygonum effectively.2. Established the method that determination of Polysaccharides of polygonum by UV spectrophotometry. That polysaccharides have been prepared to take the test solution, adding sulfuric acid- anthrone color, absorbance was measured at 490 nm conditions, the method has a good stability and reproducibility.3. By orthogonal test, established traditional processing technology and fresh processing of polygonum. That traditional medicine Polygonum process: taking Polygonum medicine(4mm diameter approximately) placed wash drug pool and then poured into water after soaking 36 h out, then bagged moistening 6h, removed,reciprocating cut drug machine cut 6-8mm thick slices, and then placed in 50 ?box-type drying machine can(about 36h); take advantage of fresh process: taking Polygonum fresh herbs, put in a box dryer and dried to a moisture content of about 60%,remove with reciprocating cut drug machine cut 6-8mm thick slices and then placed in50 ? box-type dryer(about 36h).Conclusion:1.Establish and improve the quality evaluation system can effectively control the quality of Polygoni multiflori radix and its Pieces.2. Polygonum traditional processing technology that by orthogonal test method established, has a guidance and normative role for medicine production enterprises,established that the fresh processing technology and processing technology compared to traditional origin, the process is simple, short time-consuming; higher pieces indicators prepared ingredients.3. On the basis of the fresh processing technology that optimium of polygonum in labratrary, combined with the actual situation of medicine production enterprises,through pilot production, established the fresh processing industrial production technology of polygonum is reasonably and practicable. |
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