The Effect Of Opportunistic Salpingectomy On Premenopausal Women’s Ovarian Function

Objective:Studies have shown that high grade serous ovarian cancer originated in the fallopian tubes,Salpingectomy can prevent the occurrence of ovarian cancer and other malignancies.This study is a prospective clinical trials,to study whether opportunistic salpingectomy has effect on the function of premenopausal women’s ovarian of laparoscopic hysterectomy,providing a more reliable basis for clinical application of opportunistic salpingectomy.Methods: 60 premenopausal patients were selected from Yijishan Hospital 2014.10-2015.10 due to benign uterine disease in laparoscopic supracervical hysterectomy and total laparoscopic hysterectomy,respectively.60 patients were divided randomly into 2 groups,undergoing laparoscopic supracervical hysterectomy,experimental group A with opportunistic salpingectomy,experimental group B as the control group.60 patients were divided randomly into 2 groups,undergoing total supracervical hysterectomy,experimental group C with opportunistic salpingectomy,experimental group D as the control group.Extracting all patients’ fasting blood before surgery and 3 months later in the same period of follicular.Compare the change of FSH,LH,E2.Use transvaginal ultrasound to measure the change of OV,AFC,PSV,RI before surgery and 3 months later in the same period of follicular.Results: All patients were recorded and compared operative time,blood loss and postoperative hospital stay.The differences between group A and group B in operation time,blood loss and postoperative hospital stay was not statistically significant(P>0.05).The differences between group C and group D in operation time,blood loss and postoperative hospital stay was not statistically significant(P> 0.05).FSH,LH increased significantly and E2 decreased significantly for 3 months later in the same period of follicular of all groups,and the difference has significant statistical significance(P <0.01).RI increased significantly and AFC,PSV decreased significantly measured by transvaginal ultrasound for 3 months later in the same period of follicular of all groups,and the difference has significant statistical significance(P <0.01).The difference of OV was not statistically significant(P>0.05).Neither before surgery nor after 3 months,all indicators differences between the groups were not statistically significant(P>0.05).Conclusion:Laparoscopic supracervical hysterectomy and total laparoscopic hysterectomy in premenopausal women can result in significant decline in ovarian function.But remove both fallopian tubes don not increase the difficulty of operation,nor aggravate ovarian dysfunction.Opportunistic salpingectomy can be used as fertility requirements of women against ovarian cancer and other malignancies.