Safety Evaluation And Clinical Research Of Xiangweiershi Liquid

Xiangweiershi liquid is a Chinese medicine which was made of Pogostemonis Herba,Phragmitis Rhizoma and other medicine.It mainly be used for treating warm heat diseaes. In this study we have a prliminary research in Xiangweiershi liquid with pharmacodynamics and safety evaluation, which makes basis for experimental and theoretical in clinical applications.According to Xiangweiershi liquid draft quality standard determination the medicine to evaluate product quality. The main testing project has the TLC identification, high performance liquid chromatography.The sample of Xiangweiershi liquid is stable in line with the requirements of test.Xiangweiershi liquid in the effect of heat stress resistance of bed and expanding clinical experiment, by testing the pig body of clinical disease, rectal temperature, respiratory frequency and heat shock protein, found Xiangweiershi liquid can reduce the rectal temperature, reduce the heat caused by breathing, increase the heat shock protein content in pig serum, enhance the effect of resisting heat stress, the experimental results show that Xiangweiershi liquid has therapeutic effect on pig heat stress.In the study of safety evaluation, Xiangweiershi liquid on the pig use safety and safety dosage was investigated, through the detection of clinical signs, blood biochemical indexes, Defecation, etc., prove that in per kg respectively in drinking water add Xiangweiershi liquid 15 m L, 9 m L and 3 m L of target animal pigs are safeAccroding these results, Xiangweiershi liquid has therapeutic effect to the pig heat stress, can reduce the rectal temperature, reduce the heat caused by breathing, in a safe dose range long-term use is safe.