Studies On The Catalytic Amination Of N-octanol

Aliphatic amines are important organic intermediates for the raw chemical materials and pharmaceutical industries, which have found many applications in the field of dye, pesticide, medicine, and so on. Catalytic amination of fatty alcohols is one of the most useful methods for the fabrication of these kinds of compounds. The catalytic amination of n-octanol were studied systematically in this paper.First of all, we chose copper and nickel as the main active ingredient in the catalyst, chromium, cobalt, iron, zinc and alkaline-earth metals as auxiliary active ingredient, and alumina, diatomaceous earth as well as ZSM-5 zeolite as supports to prepare a series of amination of n-octanol catalyst by coprecipitation method. The catalysts were characterized by X-ray diffraction(XRD) and scanning electron microscope(SEM). Secondly, catalytic effects in n-octanol catalyzed amination reaction were investigated. Experimental results showed that 20% Nickel & 2% Copper as the main active component, 1% ruthenium & 0.5% zinc as an auxiliary active ingredient and ?-Al2O3 as the carrier of the catalyst exhibited the best activity and the product selectivity for catalytic amination of n-octanol. At last, the catalyst was used as the optimum catalyst for catalytic amination of n-octanol and the reaction to the optimum conditions were chosen and optimized. The products were analyzed by Gas Chromatography-Mass Spectrometer(GC-MS) and the optimum process conditions were determined by reaction temperature, hydrogen pressure, sphingosine ratio and the feedgas space velocity of reaction factors. While reaction temperature was 180?, a hydrogen pressure was 2 MPa, the ratio of amine and alcohol was 10: 1, and the space velocity of the raw material gas was 85.2 h-1 as the optimized reaction conditions. The amination of n-octanol conversion rate was up to 99.5% and product selectivity was preferably 95%. Under the conditions, the catalyst could be reused continuously for a month.Through preparation and optimization of the catalysts for amination of n-octanol, as well as the reaction conditions, the necessary experimental data for the fatty amine compounds of industrial production were provided.