The Experimental Research Of Moxibustion Based On Photoacoustic Imageing Systems

In recent years,Photoacoustic imaging technology has become a new direction for researchers in the field of medical imaging, the advantages of photoacoustic imaging techniques are more obvious. It can be non-invasive imaging of biological tissue, not only for structural imaging can also be functional imaging, besides,system equipment price is relatively low. Living tissue optical absorption coefficient is different,when the laser irradiation, the tissue absorbs the laser energy to cause a change in temperature in different parts to produce ultrasound, the ultrasound is to organize the photoacoustic signal conveyed by collecting signal we can reconstruct an image, such high-contrast images of both light imaging results also combines high-resolution ultrasound. Paper to build such a photoacoustic imaging system to study Chinese medicine moxibustion, and phantom experiments by the imaging capability of the system, the paper focuses on experimental study moxibustion brain imaging in mice:1.photoacoustic tomography imaging experimental system build and testPhotoacoustic tomography is a more advanced imaging technology, under the guidance of instructors set up their own first set of University of Electronic Science and Technology of photoacoustic imaging system. To explore the imaging system reliability and image clarity, our biological tissue phantom, live animals experimentally. The effects of the system ultrasonic transducer center frequency imaging effect; by phantom experiments verify the effect of the ultrasound transducer and the test sample from the imaging effect; the effects of motor control program step for the reconstruction of the image. Set up a system in imaging experiments, the complete scan takes about 3min,laser wavelength used is 532 ns, using a stepper motor step angle of 2 degrees.2.moxibustion experimental study on rats black photoacoustic tomography systemMeanwhile, with the advancement of technology, and gradually increase the people’s awareness of health, moxibustion therapy as a natural by everyone’s attention,but also its modern scientific theories put forward new demands. Now, clinical research and moxibustion theory of neural thread moxibustion progress will study the introduction of a new realm. Using laboratory PAT system, we moxibustion mice brain activity during the structural and functional imaging. In this experiment, we will be thefirst time the feasibility of black mice were moxibustion brain imaging to verify the black rat brain imaging. After we Yongquan moxibustion black rat, black rat was observed in brain blood flow in brain blood flow after moxibustion moxibustion difference before and, looking out of moxibustion on brain regions; paper for the first time of knockout mice were moxibustion experiment, knockout mice knockout heat-sensitive gene sequences, through experimental observation of moxibustion mice are fully complete knockout, moxibustion whether the brain can cause changes in the concentration of hemoglobin in mice; explore the normal black mouse around Yongquan stimulation on brain changes in hemoglobin concentration. By moxibustion and black rat brain functional imaging provides visual experimental basis for the traditional moxibustion therapy.