Font Size: a A A

Temperature Field Numerical Analysis And Software Development Of Microwave Ablation Of Atrial Fibrillation

Posted on:2015-09-18Degree:MasterType:Thesis
Country:ChinaCandidate:F ZhaiFull Text:PDF
GTID:2298330452453447Subject:Biomedical engineering
Abstract/Summary:PDF Full Text Request
Atrial Fibrillation (AF) is the most common clinically cardiac arrhythmia. As anew technology to treat AF in surgical operation, microwave ablation therapy makecoagulate necrosis appeared in the target region and the cardiac tissue surrounding thetarget by input a certain number of microwave energy, and remove the cardiacarrhythmia. The finite element simulation as a method of numerical simulation hasbeen widely used in the study of temperature field in microwave ablation. At presentthe numerical simulation research of atrial fibrillation, the issue of epicardial fat layer,epicardial ablation, and point by point ablation are still inadequate. Moreover, in thescientific research and clinical treatment, microwave ablation surgicaldecision-making system need to be developed. This system can rapidly and exactlyprovide the results of numerical simulation according to the specific pathologicalconditions.Base on the microwave ablation of atrial fibrillation, this paper research ablationtemperature field by electromagnetic thermal coupling numerical simulation analysis.This paper studied the different factors of clinical pathology and treatment effects ontemperature field in process of microwave ablation of atrial fibrillation. Study theeffects of fat layer which out of the heart on the temperature distribution inendocardial and epicardial microwave ablation respectively. We focus on thetherapeutic schedule of point by point microwave ablation in atrial fibrillation.Establish atrial fibrillation microwave ablation surgical decision-making systemsoftware.Numerical simulation results shown:(1) the way of parallel placement is a morereasonable operation strategy of ablation, and vertically way can be used in smallscale or special position of atrial fibrillation ablation.(2) The input power andmyocardial layer thickness are the two most obvious factors the temperature field.(3)Cardiac muscle with fat layer or without have a certain impact for temperature field ofMicrowave ablation of atrial fibrillation, but the difference thickness of the fat layeralmost has negligible effect on temperature field.(4) Blood convective heat transfercoefficient have a minimal impact on temperature field in microwave ablation of atrialfibrillation.(5) In the endocardial ablation, ablation depth of50℃contour reach the 6mm at30s. But in the epicardial ablation, effective ablation area appeared after34s.(6) There is severe blood flow in the heart and epicardial ablation can’t produce transmural ablation area.(7) The best fit input power and ablation point interval was50Wand1.5cm.This paper has mainly solved numerical analysis of temperature field of atrialfibrillation in microwave ablation. Quantitative data is presented to help doctors tocarry out the treatment plan and provided the scientific basis for surgical planning.Establish atrial fibrillation microwave ablation surgical decision-making systemsoftware. By inputting patients physiological situation in the software, temperaturefield can be gotten corresponding all the operation plan. Clinicians can choose thecorresponding operation scheme according the expected temperature field.
Keywords/Search Tags:Atrial fibrillation, Microwave ablation, Temperature field, Finite elementsimulation, Database software
PDF Full Text Request
Related items