ObjectiveTo study the influence of parents’ age and related factors on congenital heart disease in children, and to provide a reference for the prevention of congenital heart disease, and to reduce the incidence of disease.MethodsCase control study method was applied. The case group was diagnosed as congenital heart disease in children’s Hospital of Shanxi Province in 2014-2015, and the control group was randomly selected for children with congenital disease in the same region. The parents of the two groups were investigated by questionnaire. Statistical analysis was performed using SPSS 20 software.ResultsUsing single factor and multiple factor Logistic regression model analysis, the final 5risk elements were determined: father’s age, mother’s age, early pregnant exposure to chemical substances, cold, and active or passive smoking. 2 protective factors: early pregnancy law taking folic acid, early pregnancy vitamin intake.ConclusionsOld parents, early pregnant exposure to chemical substances, cold, and active or passive smoking are is risk factors. Early pregnancy law taking folic acid and early pregnancy vitamin intake are protective elements. Because of the high mortality ofcongenital heart disease, the prevention should be strengthened and the mortality rate should be reduced. |