Relationships Between Serum Lipoprotein(a) And Sarcopenia In Hospitalization Old Patients

Aim: Examine the association of serum Lp(a) with sarcopenia in Chinese hospitalization old patients.Methods: We conducted this study using data from hospitalized Chinese people 60 years old and older.who were examined using DXA and measured srum Lp(a),muscle strength(grip strength) or/and physical performance(6-m usual gait speed) between 2014 and 2015. We classified the partic ipants into four sarcopenia/obesity groups based on both total body fat percentage and appendicular skeletal muscle mass.Results: The analysis included data of 528 participants. they were assigned to three groups: Normal(n=248, M/F=81/167), sarcopenia(n=70, M/F=23/47),Obesity(154, M/F=62/92), Sarcopenic Obesity(n=56, M/F=18/38).the LP(a) level of sarcopenia was significantly higher than no sarcopenia, compared with obese or no obese groups(P < 0.05). Furthermore, In the sarcopenic obesity group, the LP(a) level was highes t. Correlation analysis showed that ASM/height2 was negatively correlated with LP(a)(R=-0.121,P<0.05). Logistic regression analysis showed that sarcopenia was positively associated with LP(a)(OR=1.587,P<0.05).Conclusions : Our study shows that sarcopenia appeared to be significantly associated with Lp(a) no matter the subjects had obesity or not.