A Meta—analysis Of Efficacy And Safety Of Greenlaser Photoselective Vaporization For The Treatment Of Non-muscle Invasive Bladder Tumor

Objective:By using advantageof meta analysis, to more objectively and efficiently evaluate the therapeutic effect and security of transurethral resection of the bladder tumor resection operation and green laser selective bladder tumor vaporization operation.Methods:Selecting the domestic and foreign core periodicals published in the literature from2006 to 2015. We compare the clinical control trials of TURBT and PVBT in two surgical treatments for NMIBC. afterwards, we implement strict inclusion and discharge standards to extract the relevant indicator data, and applying the Meta-analysis method for evaluating the safety and efficacy after surgery.Results:A total of 14 clinical controlled trials were enrolled in this analysis,including 1680 patients,of whom 761 were treated with PVBT and 919 with TURBT.Meta analysis showed that mean hospital stay [SMD-2.53 d, 95%CI-3.61 to(-1.44) d,P<0.0001],postoperative catheterization Time [SMD-2.60 d, 95%CI-3.42 to(-1.77)d,P<0.0001] and postoperative bladder irrigation Time [SMD-1.23,95%CI-1.35 to(-1.12),P<0.0001] was shorter in PVBT group than the TURBT group. In the PVBT group,the Recurrence rate [OR 0.39, 95%CI 0.27 to 0.56,P<0.0001] and incidence of operation complications [OR 0.06, 95%CI 0.03 to 0.12, p<0.0001]was significantly fewer than that in the TURBT group.In terms ofoperation time(p>0.05),There was no difference in PVBT operation and TURBT operation.Conclusion:for the treatment of NMIBC, the operation of PVBT compared to TURBT won’t increaseoperative time, but will has certain advantages in the safety index, what’smore,PVBT may helpfulin reducing recurrence of NMIBC.