Construction Of Hypertension- Related Gene Biological Database Platform

Hypertension is a complex disease, With the increase of incidence of hypertension, high blood pressure and complications of hypertension serious threat to human health. Improve people’s emphasis on hypertension disease,Early prevention, early treatment for high blood pressure disease play a key role.With the continuous development of biology field, biological data constantly Increasing, a large database which of data number constantly increasing,Increase the difficulty of obtaining data.In order to facilitate the researchers more quickly and efficiently get the data you need data, to create local secondary database,And then integrate the relevant data saved into the local database.Through the data of high blood pressure and the understanding of the biological database,hypertension Related biological database is also relatively less,the contents of hypertensive biological database is not complete,In order to make the database of high blood pressure continuously update and perfect,the data of the related genes are stored in the database,can get relevant data of high blood pressure by searching,So the design of the biological database of hypertension related genes to store these related data,By Providing high blood pressure a database platform,better access to relevant gene data,The correlation of high blood pressure data research and analysis provides convenient.Hypertension related gene database in this paper, mainly come from the national center for biotechnology information(NCBI) of network database and collection experimental data, etc. According to the attribute characteristics of hypertension related gene data,the design of the database module,Mainly divided into two modules: basic biological information database and SNP database,Create related data table for each database, under the Linux operating system created hypertension related- genes of the database,create Xampp building integrated development environment,This environment is the integration of Apache server, MySQL database and PHP programming language,based on the CS technology create MySQL based on relational database,import data into the related the in the table,By using PHP and other related programming language to realize the key words of the database search,the database is also integrated the Blast search method for data retriev,Make the hypertension related database to get better application,under BioLinux system,we builds BioMart analysis platform,Configure Java environment,The study of Cytoscape, JBrowse analysis software,to screening the sample data,Genes operation the analysis and analysis of hypertension related data,Content of HIF1 a gene sequences with perl language implementation genbank graphical analysis, etc. Related of gene sequences Sequence alignment,In order to analyze the similarity between sequences.Through the use of gene related software and some methods to analyze,So that we understanding of relevant knowledge of bioinformatics have a better.