| ObjectiveTo investigate the influence of yam gruel in patients with diabetes, by observing the fasting blood glucose,2h postprandial blood glucose, serum total cholesterol, triglyceride and other indicators, such as for yam gruel in people with diabetes to provide a scientific basis for the application.MethodsAccording to the diagnosis and reception criterion,90 patients of type 1 obesity-related hypertension were recruited in this clinical trail.The research object were randomly divided into two groups,45 cases in each group.The control group were received routine health education.While those patients in the test group received yam gruel for 12 weeks.Respectively before the intervention,intervention of 8 and 12 weeks observed two groups of blood glucose(fasting blood glucose,2h postprandial blood glucose,), blood lipid(serum total cholesterol,triglycerides,high-density lipoprotein cholesterol,low density lipoprotein), waist-to-hip ratio and changes of the indexes of quality of life.Experimental group were lost 3 people,to complete the 42;The control group were lost to follow-up 9 people,completed 36.Finally included in the PP analysis of patient test group was 42 cases, control group was 36 cases;Into ITT analysis of patient group was 45 cases, control group was 45 cases.Results1. Baseline ComparisonThere were no significant difference in general condition,disease history,dietary habits life behavior and sleep habits between the two groups before the trial (P>0.05). And there were no significant difference in fasting blood glucose,2h postprandial blood glucose(2hPG),serum total cholesterol, triglycerides, high-density lipoprotein cholesterol, low density lipoprotein,WHR and quality of life(.P>0.05).The result of intention-to-treat(ITT) analysis and PP analysis was basically compatible with each other.lt showed that the two groups were comparable.2.Changes in blood glucose(1)fasting glucose:Both Intention-To-Treat and Per-protocol,12 weeks after intervention, two groups of fasting blood glucose in patients were significant (P<0.05).(2) 2h blood glucose after breakfast:Both Intention-To-Treat and Per-protocol,12 weeks after intervention, the postprandial blood glucose 2h the differences were significant (P< 0.05).3.Changes in blood lipidThe intervention group compared with control group in Intervention after 12 weeks, to PP only the TG difference was significant (P<0.05), no statistical difference in ITT,and between the two groups of TC,HDL-C and LDL-C differences had no statistical significance (P> 0.05).4.Changes in the waist, hip circumference and WHRAfter test comparison between groups:waist circumference, hip circumference between the two groups,WHR differences were not statistically significant (P>0.05).Comparison in the group:experimental group and control group in the waist, hip circumference and WHR before test were no significant change (P>0.05).5.Change in quality of life12 weeks after experiment, the experimental group patients in the physiological function, psychological spirit, treatment 3 dimension score and total score lower than the former, and differences were statistically significant (P<0.05 or P<0.01),the social dimension score compared with the experiment before there was no significant(P>0.05);Control group patients four dimension score and total score compared to before the test there was no significant difference (P>0.05);Test after comparison between the two groups:physiological function, psychological, social, and treatment of 4 dimension score and total score comparison, there were no statistically significant difference (P>0.05).Conclusions:Through the discussion of the results of this study, Constitutions can be drawn:①Yam congee with lower fasting glucose and 2h after breakfast the effect of blood sugar, could be as an aid in the treatment of patients with type 2 diabetes.②Yam gruel of lipid levels in patients with type 2 diabetes may have certain adjustment function, the effect is not sure, need to further expand the sample size for further research.③For a period of 3 months in the process of intervention, we found no adverse impact on quality of life in patients with type 2 diabetes. |
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