Clinical Analysis Of Acute Cerebral Infarction Patients With Structural Changes Of The Carotid Artery And H Type Hypertension

Objective :To investigate the relationship between the changes in the structure of the carotid artery and H-type hypertension in acute ischemic patients.Methods :247 new cases of acute cerebral infarction in from Sep, 2014 to Sep, 2015,age 38-82 years old, average age 57.73± 8.79 years. Step one: general detailed records of all patients clinical data and laboratory index results; Step two: according to the results of the ultrasonic divided into plaque group and the control group. Step three: according to the Hcy inspection results and the presence of hypertension, divided into H hypertensive groups, pure hypertension group, HHcy group, and both normal group. Plaque group and the control group as the dependent variable and carotid atherosclerosis in patients with acute cerebral infarction may form the dangerous factors as independent variable, carries on the multi-factor logistic regression analysis; High blood pressure and HHcy carotid atherosclerotic plaques in patients with acute cerebral infarction with the function of joint interaction analysis of the additive model.Results:The plaque group and control group eache group risk factors analysis: age,history of smoking,hypertension, hyperhomocysteine, LDL-C between two groups have significant difference. The multi-factor logistic regression analysis showed that age, history of high blood pressure, LDL is the acute cerebral infarction patients with carotid atherosclerotic plaque formation of the independent risk factors. The interaction analysis:hypertension, HHcy in a synergistic role in carotid atherosclerotic stiffness improved, the effect is greater than their sum of both. The intima-media thickness, distensibility of the common carotid artery, carotid artery stiffness, and blood homocysteine level all showed significant differences between patients with H-type and non-H-type hypertension(P<0.05).Conclusions:Age, history of high blood pressure, history of smoking, LDL-C are the independent risk factors of the acute cerebral infarction patients with carotid atherosclerotic stiffness improved. H high blood pressure in patients with acute cerebral infarction carotid atherosclerosis formation were greater than the danger of high blood pressure, high homocysteine levels, and the sum of both,H type hypertension more likely impair the carotid artery structure of acute ischemic stroke patients.