Effect Of Rehabilitation Exercise On In-Stent Restenosis After PCI In Patients With CHD:a Meta-Analysis

Objective To assess the effect of rehabilitation exercise on In-stent restenosis after PCI in patients with CHD.Methods Cochrane Central Register of Controlled Trials (CENTRAL), MEDLINE,Pubmed,CBM,CNKI,Wanfang Database were searched for the randomized controlled trials(RCTs) about effect of rehabilitation exercise on In-stent restenosis from database establishment time until December 31st,2015. Searching was complete on April 1st,2016.Review Manager 5.3 software was used to conduct Meta-analysis.Results A total of 9 RCTs including 944 cases were analyzed,in which 461 cases of intervention groups and 483 cases of control group. Arteriography showed 35 cases of coronary restenosis in intervention groups(7.59%),88 cases of coronary restenosis in control group(18.22%). Test for heterogeneity,P=0.30, I2=16%,homogeneity existed among these studies.The sensitivity test showed that the results of Meta-analysis had good stability,reliable data.Merge OR=0.32, 95% confidence interval(0.21,0.51).After 6-month follow-up,the rate of in-stent restenosis of intervention group was lower than that of control group(P< 0.00001).Conclusion Rehabilitation exercise could prevent the in-stent restenosis after PCI in patients with CHD.