Exercise-based Cardiac Rehabilitation For Left Ventricular Function In Acute Coronary Syndrome:A META Analysis

Objective:To evaluate the therapeutic effect and safety of exercise-based cardiac rehabilitation on left ventricular function of patients with acute coronary syndrome,using a meta-analysis approach for quantitative analysis.Methods:The data from databases of CCRCT,Embase,PubMed,CNKI,CBM,WangFang and VIP were retrieved with computers,including randomized controlled trials(RCT)about rehabilitation exercise therapy in ACS from database established time until December 2018.The effectiveness and safety of rehabilitation exercise therapy were reviewed and given a Meta-analysis by using RevMan 5.3 software.Results:There were totally 17 RCTs included involving 1416 cases.The results showed that rehabilitation exercise therapy can improve the prognosis of the patients comparing with control group.?The left ventricular ejection fraction was significantly higher than that in control group[MD=3.42,95%CI=[2.02,4.82],p<0.00001].?The distance of 6 minute walk tests was significantly longer in rehabilitation group[MD=91.8,95%CI=[84.34,99.26],p<0.00001].?The left ventricular end diastolic diameter was lower in rehabilitation group than that in control group[MD=-3.30,95%CI=[-4.93,-1.67],p<0.0001].?The resting heart rate was lower in rehabilitation group than that in control group[MD=-3.83,95%CI=[-5.99,-1.68],p<0.0005].?The recurrent acute myocardial infarction rate was lower in rehabilitation group significantly[OR=0.13,95%CI=[0.05,0.4],p=0.0003].Conclusion:According to current study results,the standardized rehabilitation exercise therapy can significantly improve the cardiac remodeling,athletic ability and reduce recurrent acute myocardial infarction in the patients with ACS.