| ObjectivesIntroduction and translation Modified Polycystic Ovary Syndrome Health Related Quality of Life Questionnaire, to assess its reliability and validity, and to explore its adaptability in China, development suited to China’s mainland population the MPCOSQ Chinese version. Examine the survival quality of patients with PCOS in China, and explore the correlation between TCM syndrome type and quality of life among women with PCOS, to provide a reference for choosing appropriate treatment.MethodsThis study adopts the method of cross-sectional survey. Obtain the consent of the original author, and introduce MPCOSQ English original scale. Organization core working group to translation, translation and culture adjustment scale, and form Chinese MPCOSQ first draft. First performed 30 cases of PCOS patients with pre-survey, to understand the feasibility of scale. According to the working group discussed again, select the final entry form official Chinese version of the questionnaire. Then 124 PCOS patients and 62 cases of healthy controls were investigated, of which 30 cases of PCOS patients in the test retest 14 days. Using SPSS17.0 statistical software for statistical data analysis, reliability and validity of the assessment scale, as well as evaluation of quality of life condition of PCOS patients. Further application PCOS TCM scale symptoms scale,124 PCOS patients according to syndrome differentiation of traditional Chinese medicine can be divided into Spleen phlegm type, phlegm and blood stasis type, kidney and blood stasis type, Kidney deficiency and liver depression type four card type, by statistical analysis to explore the different syndromes survival of patients with PCOS correlation between quality.Results1. Research shows scale recovery rate was 95%, the completion rate is 97.89%, is the average length of a completed questionnaire (10±3 min), shows its good acceptability and feasibility. The total scale Cronbach α coefficient of 0.880, each dimension Cronbach a coefficient between 0.819 0.914, retest coefficients in each dimension between 0.828 to 0.918, split-half reliability index of 0.940, the results of the above three reliability indices It shows that the scale has good reliability. Scale by factor analysis, extracted seven common factors, the cumulative contribution rate of 77.018%. Pearson correlation coefficients of each entry belongs dimension is between 0.775~0.934 (P<0.01), higher than the correlation coefficient with the non-owning dimension. These results suggested that Chinese version can produce seven dimensions (body hair, acne, body weight, mood, infertility, menstrual symptoms and menstrual predictability), with seven original English version of the same dimensions. Each dimension cases group scores were significantly lower than the healthy control group, the difference was statistically significant (P<0.01), it shows that the scale has good discriminant validity. In addition, the data show that 124 cases of patients quality of life in patients with PCOS are subject to different degrees of impact on the seven dimensions, the most important show in infertility problems.2. The impact on the general quality of life in patients with PCOS found the same age comparison showed that patients less than 20 years of menstruation can predict the dimension of quality of life was significantly lower than the more than 20 years of age, the difference was significant. And other dimensions of quality of life score was no significant difference between different age groups. different cultural levels. Different income whether married patients no significant difference in the quality of life.3. Different syndrome types in patients with PCOS survival quality comparison results show that the Spleen phlegm type the overall quality of life significantly lower than phlegm and blood stasis type、 kidney and blood stasis type、 Kidney deficiency and liver depression type; In weight dimensions, Spleen phlegm type phlegm and blood stasis type quality of life obviously lower than Kidney deficiency and liver depression type; In the dimension of infertility, Spleen phlegm type quality of life obviously lower than kidney and blood stasis type; In the dimension of emotional problems, Spleen phlegm type survival quality is significantly lower than kidney and blood stasis type, Kidney deficiency and liver depression type; In hairy, acne, menstrual symptoms, and menstrual predictability in four dimensions, the quality of life has no obvious difference between syndrome patients.Conclusion1. Chinese version MPCOSQ has good feasibility, reliability and validity, and can be used for Chinese quality PCOS patient survival assessment, provide the basis for the choice of treatment.2. PCOS patients quality of life was significantly lower than normal control group, the main factor is infertility, followed by menstrual predictability, body mass, mood, body hair, acne, menstrual symptom of the problem.3. The quality of life is different between the PCOS patients that with different types of TCM syndromes. Therefore the process in the treatment of PCOS patients, in addition to TCM different treatment should also pay attention to improving their psychological and social function, make the necessary psychological treatment and counseling, and adopt targeted individual treatment and quality of life. For spleen phlegm blockage type should also emphasize the habits and customs with good nurturance, change unhealthy dietary, physical activity long-term adherence, weight loss and other comprehensive therapy. |
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