The Clinical Efficacy And Safety Of Percutaneous Kyphoplasty With High-viscosity Cement In The Treatment Of Osteoporotic Vertebral Compression Fractures

Objective:To investigate the clinical efficacy and safety of percutaneous kyphoplasty (PKP) with high-viscosity cement versus the low-viscosity cement in the treatment of osteoporotic vertebral compression fractures (OVCF).Methods:From January 2014 to December 2015,80 patients with OVCF were treated at our department. The high-viscosity cement PKP was conducted for 40 of them (group A) while the low-viscosity cement PKP for the other 40 (group B). The 2 groups were compatible,showing no significant differences in preoperative clinical data (P>0.05). The 2 groups were compared in terms of operation time, fluoroscopy frequency, volume of injected cement, cement leakage, and Cobb angle, anterior vertebral height, visual analogue scale (VAS) score, Oswestry disability index (ODI), SF-36 score(the MOS item short from health survey), and cement filling preoperatively,3 days and 3 months postoperatively.Results:All the patients had an uneventful operation and were followed up for at least 3 months, the longest follow-up is 1 year. Compared with group B, group A reported significantly shorter operation time(Group A:39.250min±6.558 min,Group B:43.000min ±7.578 min; t=2.245,P<0.05), lower fluoroscopy frequency(Group A:16.325±2.625,Group B:14.475±2.754; t=3.075,P<0.05), less cement leakage(Group A:15%,Group B:20%). Compared with preoperation, all the patients obtained significant improvements in Cobb angle(FA=48.5954, P<0.05; FB=30.3059, P<0.05), anterior vertebral height(FA=81.7673, P<0.05; FB=85.6987, P<0.05), VAS score(FA=675.8721, P<0.05; FB=351.1755, P<0.05), ODI(FA=558.9958, P<0.05; FB=493.3445, P<0.05), and SF-36 score(FA=155.9626, P<0.05; FB=168.9281, P<0.05) after operation (all P<0.05), but there were no significant differences between the 2 groups in terms of the above items postoperatively (P>0.05).Conclusion:Both of the 2 type of cement are safe and effective treatments of OVCF, but the high-viscosity cement PKP may be more advantageous because it leads to shorter operation time and lower fluoroscopy frequency and less complications.