Effects Of Mild Moxibustion On Diabetic Peripheral Neuropathy With Stasis Resistance Vein

[Objective] The purpose of this study was to compare the difference between mild moxibustion and usual care in treating the disease which was evaluated by peripheral nerve disease related syndromes, Toronto clinical scoring system (TCSS), and indexes of blood rheology, among patients with diabetic peripheral neuropathy and blood stasis resistance syndrome.[Methods] We enrolled 60 outpatients with diabetic peripheral neuropathy and blood sta sis resistance syndrome form the endocrinology clinic, and assigned them into the interve ntion group (n=30) and the control group (n=30). In the control group, subjects had usua 1 care including diabetes education, diet control, exercise, antidiabetic treatment (physicians adjusted the regimen according to patients’ blood glucose), and psychological treatment. In the intervention group, subjects not only had usual care but also took mild moxibustion. The main points of mild moxibustion were Feishu(BL13)、Pishu (BL2 0)、Shenshu (BL23)、Zusanli(ST36). We evaluated symptoms of diabetes in order to f inde which point to use. If the subjects had symptoms in arms we used Quchi(LI11), an d Waiguan (SJ5) additionally, but if they had symptoms in legs we used Sanyinjiao (S P6), and Yanglingquan (GB34).10 min/point,3 times/week,20 times/course,2 courses. Recording peripheral neuropathy related syndromes, Toronto clinical scoring system (TCSS) score, blood rheology indexes before and after the treatment.[Results] The total effective rate of the intervention group was 76.7%, the details were that the therapy of intervention group recovered 0 case? markedly improved 1 case, the only effective result was 22 cases,7 cases showed invalid; In the control group, The tot al effective rate was 20%, recovered 0 case, markedly improved 0 case, the only effect ive result was 6 cases,24 cases showed invalid. The total effective rate in the intervent ion group is better than the control group.In the intervention group, TCM symptom score was significantly decreased after the treatment, while in the control group, there was no statistically significant difference in TCMsymptom score after the treatment. Furthermore, TCM symptom score was significan tly lower in the intervention group compared to the control group.In the intervention group, TCSS score was significantly decreased after the treatm ent, while in the control group, there was no statistically significant difference in TCSS score after the treatment. Furthermore, TCSS score was significantly lower in the interve ntion group compared to the control group.The blood flow index (whole blood low shear reduction viscosity, high shear reductive viscosity, plasma viscosity, erythrocyte aggregation index) significantly declined after the treatment in the intervention group. However, in the control group, only low shear reduction viscosity, and erythrocyte aggregation index significantly decreased. After the treatment, whole blood low shear reduction viscosity, high shear reductive viscosity, plasma viscosity, and erythrocyte aggregation index were significantly lower in the intervention group compared to the control group.[Conclusions] On the basis of conventional treatment, mild moxibustion can effectively reduce the index of blood rheology, containing whole blood low shear reduction viscosity, high shear reductive viscosity, plasma viscosity, erythrocyte aggregation index, in patients with DPN. It also relieved symptoms including limb numbness or pain, chest rib and lower back pain, and improve the TCM symptom such as insomnia. Mild moxibustion can relieve symptoms in patients with DPN. Considering the positive roles of Mild moxibustion, this treatment should be promoted in practice.