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The Clinical Features And Prognostic Factors Of Primary Intraventricular Hemorrhage

Posted on:2017-01-17Degree:MasterType:Thesis
Country:ChinaCandidate:Muhammad Hassan L HFull Text:PDF
GTID:2284330488491977Subject:Clinical medicine
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Aim:Primary intraventricular hemorrhage is a rare neurological disorder that can be defined as bleeding that is confined to the ventricular system upon presentation, without any discernible parenchymal component on computed tomography and/or Magnetic resonance imaging. My aim in this study was to analyze the presenting symptoms, risk factors associated with PIVH and the outcome in our in-hospital setting and compare the results with other similar studies conducted.Materials and methods:I retrospectively studied 40 patients, that I identified with Primary Intraventricular Hemorrhage within a period of 5 years from 2011-2015.1 reviewed the medical records, computed tomography images and excluded patients that had intraventricular hemorrhage with obvious parenchymal component as well as those with traumatic PIVH. The mean age was 44.35 ranging from 18 to 75 of which 25 were males while 15 were females.Results:Headache(n=33) was the major presenting symptom followed by nausea/vomiting (n=23), followed by Confusion (n=15), and dizziness and loss of consciousness (n=8). 11 of the patients developed Hydrocephalus (27.5%). CTA and DSA revealed AVM in 17.5% of patients. Hypertension association was found in 43.5 percent of patients. While moyamoya disease was found in 12.5%.4 of the patients (10%) died in the in-hospital setting due to worsening clinical situation after rebleeding and/or hydrocephalus. The etiology and risk factors remained unknown in 13 of the patients (32.5%). Hydrocephalus and the GCS score at presentation does affect the outcome of patients with PIVH(p<0.05). Although hypertension is an important predisposing risk factor for PIVH it does not affect the outcome of patients (p>0.05)Conclusion:Headache, overall, is the most common presenting symptom. Hypertension has the most common association with PIVH followed by AVM. Moyamoya disease was also found to have major contribution in association with PIVH...
Keywords/Search Tags:Hypertension, PIVH, Primary intraventricular hemorrhage, hydrocephalus, mRS, GCS
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