| Purpose and meaning:This study through the observation of oral Chinese medicine syndrome differentiation therapy shows constipation patients, compared with western medicine standard treatment primary symptom score in patients with constipation, colon transmission function, life quality, the effect of long-term, slow shows for syndrome differentiation of traditional Chinese medicine treatment of constipation with the tradition of simple and effective, cheap and safe therapy.Methods:the hospital doctor of spleen and stomach disease key specialty outpatient and hospitalization in patients with constipation in February 2015 to February 2016, selected in accordance with the standard diagnostic criteria, inclusion criteria, exclusion criteria) of 60 cases of patients with slow transit constipation. Due to the longer course of disease, taking into account the shedding factor, to an additional 20% of the sample size, the final confirmation of the number of cases in 72 cases.72 patients were divided into treatment group (the Chinese medicine treatment group) and control group (treated with the standard therapy group),36 cases in each group by simple random method; excluding the treatment group in the clinical data is not complete in 3 cases, half-way taking other drugs in 2 cases and lost to follow-up off in 2 cases, and ultimately into the statistical analysis of 29 cases; excluding the control group in the midway don’t cooperate in 2 cases, clinical information is not complete in 4 cases, lost to follow-up fall off in 3 cases, finally included 27 cases. Respectively to the oral Chinese medicine treatment and mo sand Billy+polyethylene glycol (peg) 4000, course of 4 weeks. Curative effect for reference in 2004, the ministry of health issued the "Chinese medicine new medicine clinical research guiding principles, main symptom curative effect evaluation standard, which involved in curative effect evaluation of major clinical symptoms include:defecation frequency, defecate difficulty, defecation time, endless defecate, excrement traits and meaning is feeling. Main therapeutic effect evaluation standard of comprehensive reference constipation symptoms rating scale, constipation patients quality of life rating scale (PAC-QOL) calculation points difference before and after treatment as compared between groups. Treatment after 1 month,2 months, 3 months follow-up records of constipation in patients with primary symptom rating scale, constipation long curative effect in the quality of life rating scale for PAC-QOL assessment. Using SPSS 18.0 statistical analysis, P<0.05 was statistically significant.Result:Two groups before treatment in patients with primary symptom of sex, age, constipation total score and quality of life score, in contrast, there was no significant statistical difference (P> 0.05), comparable.①There was no significant difference in the total curative effect between the two groups (P>0.05). In the treatment group,2 cases (6.89%), effective in 25 cases (86.21%), the total effective rate was 93.1%; the control group was markedly effective in 1 cases (3.71%), effective in 23 cases (85.19%), the total effective rate was 88.9%. Total analysis set: treatment group markedly effective in 2 cases (5.56%), effective in 25 cases (69.44%), the total effective rate was 75%; the control group was markedly effective in 1 cases (2.78%), effective in 23 cases (63.89%), the total effective rate was 66.67%.②Two groups of patients before and after treatment and follow-up of 1, March 2, group total integral comparison. Two groups of patients before and after treatment showed significant statistical differences (P<0.05). In January, February and March were compared between the treatment group and the control group showed significant difference in January, February and March were followed up (P<0.05).③Two groups of patients before and after treatment and follow-up 1,2, March group of total score of constipation between the two groups after treatment, no significant difference (P>0.05), the treatment group and control group, the curative effect is similar. Follow up: compared to the treatment group and the control group in the follow-up after 1 month and 2 months later. There was no significant difference (P>0.05); and patients were followed up for 3 months after the two groups compared with significant difference (P<0.05), that follow-up after 3 months of treatment group were better than that of the control group.④Two groups of patients before and after treatment, and follow-up of the quality of life score comparison:two groups before and after treatment (P<0.05), two groups of different treatment methods to improve the quality of life of patients with constipation. The follow-up time:two groups were P<0.05, there was significant difference between the two groups after 1, February, P>0.05, no significant difference, and after 3 months of follow-up, P<0.05, there was significant difference.Conclusion:1、Chinese medicine dialectical treats slow both transmissive constipation curative efffect is similar to western medicine.2、Treats dialectical treatment of TCM shows slow constipation in patients with simple operation, easy to accept, and stable curative efffect, has certain forward curative effect, clinical curative effect is satisfied, is beneficial to the clinical application in the future. |
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