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Relativity Research On TCM Constitution Types Of Coronary Heart Disease And Plasma Homocysteine Level

Posted on:2017-05-18Degree:MasterType:Thesis
Country:ChinaCandidate:X J CaiFull Text:PDF
GTID:2284330488454184Subject:Internal medicine of traditional Chinese medicine
Abstract/Summary:
ObjectiveThe study analyze the distribution of TCM constitution types of CHD on the clinical methods of investigation. To probe the relevance of CHD TCM constitution types and plasma homocysteine levels in order to provide an objective basis for physical differences in patients with CHD. In addition,to provide new ideas of analyzing clinical condition of patients with coronary heart disease and physical conditioning.MethodAccording to the results of coronary angiography, selected to meet the requirements of 105 patients with coronary heart disease. Based on the constitution classification standard of Chinese constitution cassification and determination established by the Chinese Medical Association, CHD patients were divided into nine kinds of physical typ-es, including gentleness, qi deficiency, yang asthenia, yin asthenia, phlegmatic hygrosis, humid heat, blood stasis, qi quality and special intrinsic quality. While filtering out 10 gentleness healthy persons as control group in the Guangzhou Military General Hospital medical population. Two groups of patients were detected in plasma homocysteine level. Using SPSS19.0 statistical software to establish a database and statistical analysis.Result1.The TCM Constitution distribution of CHD:Blood stasis 29 cases (27.6%)>Qi deficiency 21 cases(20%)>phlegmatic hygrosis 14 cases(13.3%)>humid heat 11 cases(10.5%)=yin asthenia 11 cases(10.5%)>yang asthenia 9 cases(8.6%)>qi quality 5 cases(4.8%)>gentleness 3 cases(2.9%)>special intrins-ic quality 2 cases(1.9%).2. The plasma homocysteine levels of Men patients compared with female patients, the difference was statistically significant(P<0.05).3. The plasma homocysteine levels of CHD group compared with thehealthy control group, the difference was statistically significant(P<0.05). Stable angina compared with unstable angina, the difference was statistically significant(P<0.01). Comparison of stable angina and acute myocardial infarction, the difference was statistically significant(P<0.01). Acute myocardial infarction compared with unstable angina, the difference was not statistically significant(P>0.05).4. The plasma homocysteine levels of Blood stasis, Qi deficiency, yin asthenia, phlegmatic hygrosis, humid heat compared with the healthy control group, the difference was statistically significant(P<0.05). Comparison of other physical type group and the healthy control group, the difference was not statistically significant (P>0.05).5. The plasma homocysteine levels of CHD physical types in the order of blood stasis>phlegmatic hygrosis>qideficiency>humid heat>yin asthenia>yang asthenia>gentleness>special intrinsic quality>qi quality. Between any two physical type, blood stasis compared with yin asthenia, yang asthenia, gentleness,qi quality, special intrinsic quality, the difference was statistically significant(P<0.05 or P<0.01).Comparison of blood stasis and phlegmatic hygrosis, qi deficiency, humid heat, the difference was not statist-ically significant(P>0.05).6. According to the type of physical findings, the patients were divided into two kinds of evil essence and quality of weak. Phlegmatic hygrosis, humid heat, blood stasis, qi deficiency group of patients were assigned to the evil-essence, qi deficiency, yang asthenia, yin asthenia patients were assigned to the weak quality group. The plasma homocysteine levels of evil essence and weak quality group, the difference was statistically significant (P<0.05).Conclusion1. Blood stasis, qi deficiency, Phlegmatic hygrosis physical type most widely distributed in CHD Patients.2. The plasma homocysteine levels of male patients with CHD were higher than females.3. The plasma homocysteine levels of CHD were significantly higher than the healthy control group. The plasma homocysteine levels of Unstable Angina and Acute Myocardial Infarction patients were higher thanstable angina.4. The plasma homocysteine levels of qidef iciency, Yin asthenia, Phlegmatic hygrosis, humid heat, blood stasis were higher than the healthy control group.5. The plasma homocysteine levels of blood stasis were higher than Yin asthenia, Yang asthenia, qi quality, gentleness and special intrinsic quality groups.6. The plasma homocysteine levels of evil essence with CHD was higher than the weak quality group.
Keywords/Search Tags:Coronary Heart Disease, TCM constitution, Homocysteine
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