A Study Of Functional Magnetic Resonance Imaging（fMRI）And The Clinical Effect In Stroke Patient Using Lifting Yang To Dredging Du Meridian Manipulation

Objective: To assess the clinical effect and central mechanism of acupuncture treat stroke using lifting yang to dredging Du meridian manipulation by observing different acupuncture manipulation improve limb motor function and affect resting state functional magnetic resonance imaging(fMRI).Methods: 90 patients were divided into lifting yang and dredging Du meridian manipulation group(30 cases), activating brain and regaining consciousness group(30 cases) and conventional treatment group(30 cases) with random number table. The group of lifting yang and dredging Du meridian manipulation choose acupuncture treatment and conventional treatment. The main acupoints were as follows: ren zhong, bai hui, feng chi, da zhui, zhi yang, ming men, tong tian, luo que, tian zhu. The matching acupoint were points from Du meridian and back-shu acupoint. The group of activating brain and regaining consciousness using acupuncture treatment and conventional treatment. The main acupoints were as follows: nei guan, ren zhong, san yin jiao, ji quan, chi ze, wei zhong. The matching acupoint were as follow: feng chi, wan gu, yi feng, he gu, shang lian quan, jin jin, yu ye, qiu xu. The conventional treatment group only received conventional treatment. After 14 days of treatment. Collecting the Barthel score, Fugl-Meyer score, resting state functional magnetic resonance imaging and analyze all of the indexes.Results:(1) Compare the Barthel score and Fugl-Meyer score of the 3 groups(P<0.001), with statistical significance.(2) Compare the Barthel score and Fugl-Meyer score between lifting yang and dredging Du meridian manipulation group and activating brain and regaining consciousness group,(p>0.05), without statistical significance.(3) Compare the Barthel score and Fugl-Meyer score between lifting yang and dredging Du meridian manipulation group and conventional treatment group,(p<0.05), with statistical significance.(4) Compare the Barthel score and Fugl-Meyer score between lifting yang and dredging Du meridian manipulation group and activating brain and regaining consciousness group,(p<0.05), with statistical significance.(5) In lifting yang and dredging Du meridian manipulation group, regions that differences exist of Re Ho variation after acupuncture treatment are as follow, claustrum, inferior parietal lobule, superior parietal lobule, superior frontal gyrus, precentral gyrus, medial frontal gyrus,(p<0.05), with statistical significance.(6) In activating brain and regaining consciousness group, regions that differences exist of Re Ho variation after acupuncture treatment are as follow, claustrum, putamen, inferior parietal lobule, superior frontal gyrus, precentral gyrus,(p<0.05), with statistical significance.(7) In conventional treatment group, regions that differences exist of Re Ho variation after acupuncture treatment are as follow, supplementary motor areas, precentral gyrus, inferior frontal gyrus, putamen, temporal lobe,(p<0.05), with statistical significance.Conclusion: This study suggests that curative effect of conventional treatment combine with acupuncture treatment is better than conventional treatment. There is significant curative effect in variation activities of daily life and limb function by lifting yang and dredging Du meridian manipulation. The results showed that there is equivalent effect in variation activities of daily life and limb function between lifting yang and dredging Du meridian manipulation and activating brain and regaining consciousness manipulation. Acupuncture can lead to Re Ho change in claustrum, inferior parietal lobule, putamen and precentral gyrus, this maybe the central mechanism of acupuncture treat stroke.