Clinical Analysis Of Obstructive Sleep-apnea Hypopnea Syndrome And Obesity Hypoventilation Syndrome

Objective Obesity is a common problem in modern society, and it is closely related to many diseases, poses a threat to human health, the impact of obesity on the respiratory system is obviously. Obstructive sleep apnea is a respiratory disease closely related to obesity, and obesity hypoventilation syndrome is a closely associated with obesity in respiratory disorders. Between the two is very similar, but they are two completely different kinds of diseases, OSAHS has received more and more attention, but the obesity hypoventilation syndrome diagnosis rate is not high. Caused by obesity obesity hypoventilation syndrome, there is often a merger with OSAHS. The subject of our department for multichannel sleep monitoring of patients screened in patients with OSAHS, according to whether with OHS, divided into OSAHS and OSAHS patients with OHS group were detected related indexes of two groups, and analyzed.Methods Blood gas analysis and obesity screening for PSG patients diagnosed with OSAHS. According to the results of the screening of simple OSAHS group, combined with the presence of OHS and OSAHS group. The patients in each group. Its physical measurement index(BMI, neck circumference, waist circumference, waist to hip ratio, etc.), arterial blood gas levels(PO2, p CO2), lung function(FEV1, FEV1 / FVC, MVV, VC) and polysomnography(AHI, La, msao, lsao2, Sa O2, SIT90%), echocardiography(pulmonary artery pressure, right heart function, etc.), the association between each evaluation index, between the groups correlation analysis was carried out.Results(1) two groups of patients aged 37-60 years old, There was no significant difference in age between the two groups(P>0.05). OSAHS combined with BMI group OHS was higher than that of simple OSAHS group(P<0.05)(2) the results of measurement in physical indexes of the two groups, and differences have statistical significance(P < 0.05); in OSAHS patients with OHS group of neck circumference, waist circumference and waist to hip ratio is higher than that of pure OSAHS group(respectively 39.11± 1.72VS41.17 ± 2.42,101.3± 7.78VS104.15 ± 6.53,0.93 ± 0.12VS0.99 ± 0.23).(3) the results of arterial blood gas analysis of two groups, only OSAHS patients with daytime blood oxygen and blood carbon dioxide is lower than that of OSAHS with OHS were statistically significant(P<0.05).(4) the group echocardiography compared to pure OSAHS group tricuspid regurgitation, pulmonary hypertension, right ventricular hypertrophy, right ventricular enlargement and lower incidence of OSAHS patients with OHS group, the difference between the results of two groups of patients with statistical significance(P =0.0271, P < 0.05)(5) of the two groups of sleep and blood oxygen monitoring results, the difference between the two groups of patients with AHI, La, arterial oxygen saturation based value and lsao2 no significant(P > 0.1), OSAHAS with OHS patients msao, SIT90% decreased more obviously(P < 0.01), there was significant difference(P0.05)..(6) two groups of pulmonary function test comparison, FEV1/FVC% had no significant difference(P>0.1). OSAHS with OHS were FEV1%, MVV% and VC% were lower than that in the OSAHS group, there were significant differences(P<0.05).Conclusion OSAHS patients are easy to merge OHS and easy to be ignored. There were more severe complications in patients with OSAHS than those with OHS alone in patients with OSAHS. Therefore, it is necessary to attach importance to the combination of OSAHS patients with OHS to be active treatment.