The Correlation Between Postprandial Hypotension And Heart Rate Variability In Elderly Patients With Essential Hypertension

Objective: The purposes of this study were to observe our hospitalized elderly patients with essential hypertension and understand the incidence rate and clinical features of the postprandial hypotension(PPH), to analysis the relationship between PPH and heart rate variability(HRV) in patients with essential hypertension. Methods: The study was performed on 133 cases of essential hypertension patients with the complete medical records in the Second Affiliated hospital of Xinjiang Medical University from March 2014 to October 2015, the patients were divided into two groups according to the postprandial hypotension diagnosis standard: postprandial hypotension group(PPH) and non-postprandial hypotension group(NPPH), comparing the difference between the two groups of patients with HRV index. Results: The detection rate of PPH was 61.65%(82/133). Compared with NPPH group, the SDNN, PNN50, RMSSD were significantly decreased(P<0.05). The decreased maximum values of SBP after meal were correlation with age(r=0.736, P<0.001), duration of hypertension(r=0.905, P<0.001), the levels of SBP before meals(r=0.607, P<0.001), SDNN(r=0.126, P=0.149) and PNN50(r=0.244, P=0.005). Logistic regression analysis showed that age, duration of hypertension, diabetes increased risk of PPH.Conclusion: PPH is a common disease in elderly essential hypertensive patients and PPH patients with reduced heart rate variability, which suggests that the postprandial hypotension in elderly hypertensive patients is partly caused by the disorder of cardiovascular autonomic function.