| Objective:This subject is to use real spleen flavored drink paste to Yang deficiency in the treatment of chronic heart failure patients, hoping to health intervention in patients with heart failure, to improve the signs and symptoms of chronic heart failure patients, improve patient quality of life, the purpose of improving heart function. Methods:Will be up to the standard of diagnosis in 73 cases of Yang deficiency chronic heart failure patients were divided into treatment group and control group. Control group was treated with routine western medicine, the treatment group on the basis of control group, and treated with real spleen flavored drink paste, treatment after 3 months, respectively, to observe and compare the two groups before and after treatment in patients with heart failure left ventricular diastolic diameter(LVEDd), left ventricular ejection fraction(EF), stroke volume(SV), cardiac output(CO), cardiac index(CI), b-type brain natriuretic peptide precursor(pro- BNP), heart rate(HR), SBP(systolic pressure), myocardial oxygen consumption(RPP), 6 minutes walk test(6 MWDS), TCM symptoms, the quality of life scale(MLHFQ), Yang deficiency of Minnesota heart failure the change of the respect such as quality score, and all the indexes between the two groups after treatment.(conventional western medicine treatment including ACEI and ARB, beta blockers, Aldosterone receptor antagonist and diuretics. Flavored drink spleen paste composition: chuan fu pian 300 g, hou pu 150 g, chao mu gua 100 g, bing lan 200 g, fu ling 400 g,pao jiang 100 g,mu xiang 60 g, ze xie150 g, pei lian120 g, chao bai zhu150 g,chuan lian30 g, cao guo20, sheng jiang400 g,sheng cao60 g) Result:1. Compared two groups of patients with cardiac function indexes before and after treatment, the treatment group echocardiographic indexes LVEDd, EF, SV, CO, CI compared before and after treatment, there were significant differences(P < 0.01); Whereas the control index of cardiac ultrasound LVEDd, EF, CI there are differences before and after the treatment(P < 0.05); Two groups of Pro- BNP compared before and after the treatment are obvious difference(P < 0.05), Pro- BNP declined significantly. Compared two groups of treatment of middle of the back function index, including CI, there are differences between the Pro- BNP(P < 0.05), EF has significant difference(P < 0.01), the treatment group is better than the control group.2. The two groups before and after treatment in patients with exercise tolerance index HR, SBP, RPP, 6 MWDS compared all have significant difference(P < 0.05). Exercise tolerance index compared two groups of patients after treatment: HR, SBP, RPP compared after treatment had no obvious difference(P > 0.05). Compared in the two groups after treatment 6 MWDS difference(P < 0.05), the treatment group is better than the control group.3. The two groups before and after treatment in patients with body, emotion situation, otherwise, all have significant difference(P < 0.01). Body situation, emotion, the two groups after treating, in comparison with other conditions have difference(P < 0.05).4. The TCM syndrome before and after treatment in both groups: the treatment group and control group all can improve Yang quality of patients with heart failure heart palpitations, shortness of breath, floating face limb swelling, bosom frowsty, asthma, cough up phlegm, less urine, abdominal distension and other symptoms; Two groups of treatment of heart palpitations, shortness of breath, floating face limb swelling, asthma, less urine, abdominal distension syndrome before and after treatment and compared(P < 0.01), two groups of chest tightness comparison before and after the treatment(P < 0.05); Cough up phlegm treatment group comparison before and after the treatment(P < 0.01), while the control group cough up phlegm comparison before and after the treatment(P < 0.05). Treatment group can also improve the weakness, spontaneous perspiration, cold, cough, and cold limbs symptoms such as irritability, including weak cold, cough, and cold limbs comparison before and after the treatment(P < 0.01), cough, irritable compared before and after treatment(P < 0.05). Compared two groups of patients with TCM syndrome curative effect: the treatment group and control group in improving heart palpitations, shortness of breath, floating face limb swelling, bosom frowsty, cough up phlegm, less urine, abdominal distension wait for a symptom curative effect quite(P > 0.05); For lack of power, cold symptoms such as asthma, cough, and cold limbs treatment group curative effect is better than that of control group, including fatigue, asthma, aversion to cold, and cold limbs comparative effectiveness comparative effectiveness(P < 0.01), cough(P < 0.05).5. Yang qualitative comparison before and after treatment in both groups, the treatment group Yang quality scores significantly lower earlier, comparison before and after treatment(P < 0.01); While the control group after treatment Yang qualitative transformation score lower not obvious(p > 0.05). Conclusion:1. Two groups of patients after treatment all can improve the cardiac function indexes. Combined with spleen drink paste can be improved significantly after treatment in patients with hf LVEDd, EF, SV, CO, CI, and Pro- BNP, and use pure western medicine treatment can improve the LVEDd in patients with heart failure, EF, CI, Pro- BNP. Instructions and spleen treatment effect is better than that of pure wine using western medicine treatment.2. Two groups of treatment all can improve the HR, SBP, RPP, 6 MWDS, one in improving the curative effect on heart failure patients with HR, SBP, RPP, six MWDS in improving with spleen is added when drinking paste treatment is better than that using pure western medicine treatment.3. The two groups of treatment all can improve the patients’ body situation, mood, other condition, compared the two groups after treatment, the treatment group to improve the quality of life is better than that of control group, prompt and treated with spleen drink paste in the aspect of improving the quality of life for patients with heart failure is better than that using pure western medicine treatment.4. Two groups of treatment all can improve Yang quality heart failure in patients with heart palpitations, shortness of breath, floating face limb swelling, bosom frowsty, asthma, cough up phlegm, less urine, abdominal distension and other symptoms integral; Two of these treatments for heart palpitations, shortness of breath, floating face limb swelling, asthma, less urine, abdominal distension and other improvement are relatively obvious, the treatment group to cough up phlegm treatment is better than the control group. Treatment group can also improve the weak cold, spontaneous sweating, cough, and cold limbs, symptoms such as irritability, integral, the weak cold, cough, and cold limbs evident improvement. Prompt and treated with spleen drink paste on improve TCM symptoms in patients with heart failure is better than simply use western medicine.5. Compared two groups of patients with TCM syndrome curative effect: the treatment group and control group in improving heart palpitations, shortness of breath, floating face limb swelling, bosom frowsty, cough up phlegm, less urine, abdominal distension and other symptoms are effective and curative effect quite; For lack of power, cold symptoms such as asthma, cough, and cold limbs to improve curative effect of treatment group is better than the control group. Prompt and treated with spleen drink paste on improve TCM symptoms in patients with heart failure is better than simply use western medicine.6. To Yang deficiency, Yang deficiency treatment group after treatment quality improved significantly; While the control group to improve is not obvious. Description and treatment with spleen drink paste in improving effect on heart failure in patients with Yang deficiency constitution is better than that using pure western medicine treatment.To sum up, the preliminary clinical observation results show that in the western medicine therapy on the basis of the use of spleen Yang deficiency quality drink paste heart failure is more effective. Its total effective rate was higher than using pure western medicine treatment of effectiveness, from physical therapy of heart failure, on the basis of western medicine treatment can significantly improve the patients’ symptoms, signs, improves cardiac function in patients and 6 minutes walk test, and improve the patients quality of life, make the patients back to family and society better, worthy of popularization in clinic. |
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