The Influence To The Efficacy Of COPD Patients With Respiratory Failure In Different Oxygen Flow Oxygen Inhalation

Objective:For chronic obstructive pulmonary disease (chronic obstructive pulmonary diseases, COPD) (hereinafter referred to as COPD) combination of respiratory failure patients, in its oxygen flooding the therapeutic efficacy of atomization inhalation in the treatment, respectively adopt high, medium and low three oxygen flow rate, by observing the therapeutic effect under different oxygen flow pattern for the most reasonable flow of oxygen, oxygen displacement of COPD with respiratory failure patients oxygen atomization inhalation clinical operation provide exactly the right flow data, lay a foundation for the security of the nursing procedures.Methods:On June 6,2015-November 2015 randomly selected in shandong province, a 3 armour hospital respiratory hospital 90 cases of copd with respiratory failure patients, will be selected by random number table method in 90 cases of COPD combined with respiratory failure were randomly divided into three groups, low oxygen flow group (oxygen flow 61/min), oxygen flow rate in the group (oxygen flow 71/min) and high oxygen flow group (oxygen flow 81/min),30 cases in each group. Three groups all take the same instruments under oxygen atomization inhalation therapy, in addition to the different oxygen flow rate, other operations are the same. Using general sociology of three groups of patients on admission information collected questionnaires (gender, age, nationality, occupation, level of education), the dyspnea scale (MRC) classification, st George’s respiratory questionnaire (SGRQ) blood gas analyzer, collect medical data of three groups of patients on admission (atomization inhalation therapy history, course and grade of difficulty in breathing, blood gas analysis, vital signs, respiratory disease history, smoking history, history of allergies). Three groups of patients with medical atomizer in all use the same oxygen atomization inhalation therapy displacement under different oxygen flow rate,2 times/d,7 d continuous treatment observation. Statistical MRC classifying three groups of patients after treatment, again carries on the SGRQ scores, between groups transverse comparison at the same time analysis compared with before treatment, blood gas analysis to observe CO2 retention. Were observed before and after treatment in three groups of patient’s heart rate and breathing rate changes. Using SPSS 17.0 software package for the data from investigation for entry and statistical analysis.Results:1.Three groups of patients on admission does not exist in the baseline socio-demographic variables and other medical variables baseline survey results statistically significant difference (p> 0.05), similar to the MRC and SGRQ score classification result, there is no significant difference (p> 0.05) among the three groups were comparable.2.Three groups of patients after treatment 7d, oxygen flow 7L/min MRC group in the overall classification is superior to the other two groups, the difference was statistically significant (p<0.05), oxygen flow 6L/min group and oxygen flow 8L/ min MRC group in the overall classification were similar, the difference was not statistically significant (p> 0.05). SGRQ scores showed oxygen flow 7L/min in patients to treat respiratory symptoms 7d, activity, the disease affects three parts oxygen flow rates than the 6L/min group and oxygen flow 8L/min group is significantly lower, the difference was statistically significant (p<0.05). Blood gas analysis test results showed that the three groups of patients after treatment 7d pH value were all increased, and the control compared with before treatment, the differences were significant (p<0.05); but on statistical data, the three groups no significant difference between the control, there is no statistically significant (p> 0.05); three groups of patients PaCO2 value 7d are decreased oxygen flow 7L/min group compared with the other two groups before treatment and after treatment, the difference statistically significant (p<0.05), after oxygen 7d driving tips atomized inhalation therapy, CO2 retention of the three groups of patients were improved the situation, but to improve the oxygen flow 7L/min group effect is more ideal; three groups of patients 7d after the value of PaO2, PaO2/FiO2 values were elevated in oxygen flow 7L/min compared before treatment and after treatment and the other two groups, the difference was statistically significant (p<0.05), after oxygen flooding prompted the fog 7d after inhalation of three groups of patients with hypoxia phenomenon were improved, but the effect of improving oxygen flow 7L/min group even better. After the oxygen flow 6L/min group and oxygen flow 7L/min heart rate and respiratory rate treatment group compared with that before treatment, the difference was not statistically significant (p> 0.05), but the oxygen flow 8L/min group two indexes significant change, other patient groups compared to the previous treatment, statistically significant differences (p<0.05).Conclusions:1.United in copd patients with respiratory failure in the process of oxygen atomization inhalation displacement, using 7 1/min flow of oxygen in improving patients’degree of difficulty in breathing, condition, quality of life and psychological status has significant advantages, effect is better than that of other oxygen atomization inhalation flow effect.2.61/min,7 1/min,81/min three oxygen atomization inhalation flow can effectively improve the combination of respiratory failure in patients with copd CO2 retention, and with the increase of the oxygen flow rate, will not cause the CO2 retention risk, compared with 61/min,81/min two oxygen flow patterns,71/min to improve patients with CO2 retention and reduce anoxia circumstance of the effect is more ideal.3.6 l/min,71/min of copd with respiratory failure in patients with heart rate and breathing rate is smaller, the influence of 81/min oxygen atomization inhalation flow is likely to be a harmful effect on the patient’s heart rate and breathing rate, heart rate and breathing rate is accelerated, thus affecting patient tolerance, atomization inhalation treatment interruption.