| Background:Thyroid disease is common disease and frequently-occurring disease of endocrine system,it is a group of diseases including thyroid function, morphology and organization structure of the pathological change. In recent years, the prevalence of thyroid disease showed a trend of increased year by year, according to reports its prevalence rate is 36%. Especially the thyroid cancer, serious threat to people’s life. The existing research results prove that thyroid disease risk factors includ heredity, infection, iodine, stress, sex and age, etc. Long-term intake of iodine excess or transient intake, are likely to produce harm to health. And statistics show that clinical medical personnel thyroid disease incidence was significantly higher than the general population. Most researchers have attributed this phenomenon to the medical staff working pressure, mental tension, etc. But clinical medical staff in the working process need to contact a lot of iodine disinfectants. One of the most commonly used iodine disinfectant is povidone iodine, the iodine in i povidone iodine is one of the important environmental factors that affect thyroid morphology function. Because of elemental iodine volatile, iodine in hospital work environments should be higher than that of other environmental, But there is little studies about medical workers exposure to iodine and thyroid disease, So we chose to investigate iodine exposure and thyroid disease of the medical staff and analyze it using statistical correlation analysis method.Objective:Through the survey and statistical analysis to determine whether the clinical medical personnel are thyroid diseases high-risk groups, the high prevalence of thyroid disease and their work environment does have relevance, Etiology assumptions can be made for further research, And to take appropriate intervention measures to prevent thyroid disease.Methods:Select clinical medical staff 978 people, in close contact with iodine disinfectants more than one year, as study group, from Yantai Affiliated Hospital of Binzhou Medical University, select 784 people with the teaching task of teachers from No.1 Senior High School,Muping,Shandong Province and MuPing experimental middle school, as control group.Investigation methods include thyroid ultrasonography and questionnaire. Survey content includes the following aspects:(1) general situation; (2) stress of job; (3) The iodine disinfectants dosage in each department of the hospital; (4) The examination results of the thyroid ultrasonography.All data were analyzed by SPSS 17.0 statistical software, using descriptive statistics, chi-square test, etc.Main results:(1) No significant difference was found in the general data between the study group and the control group, the two groups were comparable.(2) Medical group and secondary school teachers group work pressure scores were 34.02±7.10,33.41±6.6, no significant difference was found in the survey score of job stress between the study group and the control group (P>0.05), the two groups were comparable.(3) The overall prevalence of the medical group was 50.31%, significantly higher than the group of teachers (38.9%) (P<0.01), significantly higher than that reported in the literature of the prevalence in the general population (P <0.01), male prevalence (32.00%) was significantly lower than the female prevalence rate (61.55%), the difference was statistically significant (P<0.01)(4) Use stratified analysis method to analyze the prevalenc of medical staff group and high school teachers group, the prevalence of medical staff group was not equal between each layer or not all equa, and the prevalence of high school teachers group had no obvious difference between each layer. The two layers of stratified prevalence comparison, less than 10 years seniority, differences in the prevalence of the medical group and teacher groups was not statistically significant (P> 0.05); After more than 10 years seniority, medical group was significantly higher than the teachers group, the difference was statistically significant (P<0.01); Length of service over 20 years, the prevalence rate of the medical group is still higher than of teachers group, but the difference was significantly better than 10 to 19 years of service segment significantly (P <0.05).(5) The dosage of the iodine disinfectants in different departments of medical group had significant difference, and the prevalence of thyroid disease had significant difference too, the difference was statistically significant (P<0.05). the prevalence of thyroid disease is higher in the department with more iodine disinfectant dosage, the difference was statistically significant (P<0.05)(6) The total prevalence (50.31%), the prevalence of different genders (male 32.00%, female 61.55%) and the prevalence of each age group were all higher in medical group, than which in high school teachers group (total 38.90%, male 24.54%, female 46.41%), the difference was statistically significant (P<0.05)ConclusionsThe prevalence of thyroid disease was significantly higher in medical staff group than which in general population and high school teachers group, this high prevalence has close correlation with the iodine exposure in their work environment, the more serious the iodine exposure, the higher the prevalence, the influence was most obvious in 30 to 40 years old age group. Hospitals should take positive and effective measures to protect medical staff, prevent of thyroid disease. |
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