Analysis Of The Causes And Related Factors Of Upper Gastrointestinal Bleeding

Objective:A retrospective analysis of upper gastrointestinal bleeding patients’ s etiological composition,the relationship with age, sex,and season, the variety in 6 years in the Second Affiliated Hospital of Jilin Universityn University from 2009 to 2014 for a better understanding of the incidence of upper gastrointestinal bleeding and changes in disease status in the area in recent years,strengthening the clinical work for doctors knowledge of upper gastrointestinal bleeding of the clinical doctors,which can guide clinicians to find the causes of upper gastrointestinal bleeding quickly and accurately and make judgment and formulate reasonable clinical intervention measures, improve the prognosis and reduce mortality rate, be beneficial to the health education for patients, reduce the incidence and recurrence rate.Methods:In this study 2532 cases of upper gastrointestinal bleeding patients’ s clinical data were collected in the Second Affiliated Hospital of Jilin Universityn University Hospital from January 2009 to December 2014, of which 1510 cases were used after selected by inclusion criteria, exclusion criteria.Then we statisticed the causes of disease, age, sex, time of onset, the mortality rate, examination method and so on.,designed and improved the upper digestive tract bleeding case data registration form and recorded one by one, collated and summarized the characteristics of each variable,analysed the variation of common causes of patients with upper gastrointestinal bleeding and its relationship with sex, age, season in 6-year period.All the data are analysed and processed by SPSS18.0 statistical software, chi-square test was used to compare the sample rate, P <0.05 has statistically significant,P < 0.01 hassignificant statistical difference.Results:In this study, 1.Patients with duodenal ulcer, gastric ulcer, esophageal varices,acute gastric mucosal lesion, stomach,were five main causes of upper gastrointestinal bleeding. 2.Male patients were more than female, Male patients were significantly younger than female patients(P <0.01), There was no significant difference between male and female patients with gastric ulcer, esophageal and gastric varices and gastric cancer(P >0.05), Male patients were more likely to suffer from duodenal ulcer(P<0.05), Female patients were more likely to suffer from acute gastric mucosal lesions(P <0.05). 3.Characteristic clinical manifestation is mainly melena. 4.The mortality rate of male patients with esophageal and gastric varices was higher than that of female patients during hospitalization(P <0.05),the difference was statistically significant. 5.In this study, the incidence rate of erosive esophagitis was decreasing year by year. Other reasons(such as vascular disease, blood disease, uremia, etc.)incidence rate increased year by year. After chi square test c2=45.749 p=0.000< 0.05,with statistical significance. 6.The proportion of elderly patients with upper gastrointestinal bleeding from 2009 to 2014 showed an increasing trend year by year,while the proportion of young group showed a trend of decreasing year by year. 7.Duodenal ulcer incidence rate of young patients was the highest, followed by middle-aged patients, elderly patients incidence rate lowest(P < 0.05); gastric ulcer incidence rate of youth group was the lowest(P < 0.05); esophageal and gastric varices incidence rate middle age group was the highest(P < 0.05); the incidence of gastric cancer rate elderly group was the highest(P < 0.05). 8. In different seasons,the incidence of gastric ulcer rate in spring and winter to lower than in summer and autumn(P < 0.05); esophageal and gastric varices incidence rate was highest in winter(P < 0.05); acute gastric mucosal lesion incidence in spring to higher than that of summer and winter(P < 0.05); gastric cancer incidence in summer was the lowest(P< 0.05).Conclusion:Through this study of analysis of 1510 cases of upper gastrointestinal bleeding p atients in Changchun and the surrounding area in 6 years we found: 1.Duodenal ulcer,gastric ulcer, esophageal varices, acute gastric mucosal lesion, gastric cancer were the main causes of upper gastrointestinal bleeding. 2.Duodenal ulcer which causes the up per gastrointestinal bleeding was male dominated, while acute gastric mucosal reasulti ng in upper gastrointestinal bleeding was female dominated. 3.The incidence rate of u pper gastrointestinal bleeding in the elderly group whose main bleeding cause is gastri c ulcer showed an increasing trend year by year, while the incidence rate of the youth group showed a decreasing trend year by year. 4.In spring, summer and winter, duode nal ulcer was the main cause of bleeding, and the main cause of bleeding in autumnwa s gastric ulcer.