The Clinical Observation Of Treatment Of Mild Cognitive Dysfunction Under The Theory Of "JingXie"

purposeThrough comprehensive evaluation less treating neurological deficiency MCI and Dan decoction of four drugs Yin blood insufficient clinical curative effect of MCI, medication cost effect analysis and security, and to explore "kidney essence loss caused by god does not have" and "Yin blood born not lead to brain god along with" caused by the Chinese medicine treatment feasibility of MCI for TCM clinical "JingXie" under the theory of MCI provides safe and effective treatment.methodsAccording to the principle of randomized, controlled by the diagnostic criteria, inclusion criteria, exclusion criteria of kidney essence deficiency,81 were randomly divided into treatment group (40 cases and control group in 41 cases,85 cases of Yin blood insufficient 43 cases were randomly divided into treatment group and control group,42 cases. Treatment group kidney essence deficiency and Yin blood insufficient groups, respectively, to be Decoction for truning young and decoction of four drugs avoid Fried preparation a blunt, blunt one 100 ml,3 times a day. Both the control group were oral donepezil HCL 5 mg/times,1 time/d, oral before sleep. Drug efficacy test after February, observe the four groups before and after treatment in patients with MOCA rating scale, ADAS. Cog scale score and TCM symptom score.The resultsGeneral data of this study is to eventually into the kidney essence deficiency in patients with a total of 77 people, the treatment group 39 people, control group 38 people. Yin blood insufficient patients,83,41 treatment group, control group 42 people. After statistics analysis, comparison between groups of the patient’s age, gender, course there was no significant difference (P> 0.05).Kidney essence deficiency patients 8 weeks after treatment: treatment group (MOCA score, ADAS. Cog score and TCM symptom score compared with before treatment had significant difference (P< 0.05); Control group MOCA score, ADAS. Cog score compared with before treatment had significant difference (P< 0.05), the TCM symptom score compared with before treatment there was no significant difference (P> 0.05); Treatment group compared with the control group after treatment ADAS. Cog score and TCM symptom score and score had significant difference (P< 0.05), MOCA score there was no significant difference (P> 0.05).Yin blood insufficient patients 8 weeks after treatment:treatment group MOCA score, ADAS. Cog score and TCM symptom score compared with before treatment had significant difference (P< 0.05); Control group MOCA score, ADAS. Cog score compared with before treatment had significant difference (P< 0.05), the TCM symptom score compared with before treatment there was no significant difference (P> 0.05); Treatment group compared with the control group after treatment of TCM symptom score and score had significant difference (P< 0.05), MOCA score, ADAS. Cog score there was no significant difference (P> 0.05).Comprehensive curative effect comparison:kidney essence deficiency treatment group total effectiveness 87.18%, control group total effectiveness 76.32%, comprehensive efficacy compared the two groups have significant difference (P< 0.05); Yin blood treatment group total effectiveness 78.05%, control group total effective rate 76.19%, two groups of comprehensive efficacy was no significant difference (P> 0.05). conclusionDecoction for truning young and decoction of four drugs in the treatment of mild cognitive dysfunction is effective; Decoction for truning young can obviously improve clinical symptoms in patients with MCI, Less economic cost decoction of four drugs; Decoction for truning young and decoction of four drugs in maintaining a stable condition, prevent illness, have certain advantages; Decoction for truning young and decoction of four drugs has no obvious side effects, drug safety. In conclusion, this study preliminarily proved Decoction for truning young and decoction of four drugs in the treatment of kidney essence deficiency and Yin blood insufficient MCI, curative effect, safe and worthy of clinical popularization and application. And studies have shown that less based on using SIWU soup and Dan "JingXie" dialectical treatment of MCI has obvious curative effect, also provide a basis for research in the theoretical treatment clinical MCI.