Clinical Observation Of The Treatment Of Functional Indigestion With Intermingled Heat And Cold Due To Spleen Deficiency And Qi Stagnation Via Newly-formulated Distension-reliving Decoction (Xiao Pi Tang)

Objective:Eliminate the new hypothesis of this study was to observe the garden in the treatment of pixu(spleen deficient) and qi stagnation, fever type mixed functional dyspepsia clinical efficacy and safety, and the results of the experiment are analyzed and expounded, from two aspects of theory and academic ideas to explore and summarize the function mechanism, provide objective basis for Chinese medicine in the treatment of functional dyspepsia.Methods:Choice from December 2014 to October 2015- taiyuan city Chinese medicine hospital in accordance with functional dyspepsia and pixu(spleen deficient), disease and fever type of 60 patients with diagnosis of traditional Chinese and western medicine outpatient service, mixed were randomly divided into treatment group and control group, treatment group 30 cases and control group 30 cases, two groups of patients with general information and symptom score before treatment, etc, compared with no statistical difference(P > 0.05).Treatment group with traditional Chinese medicine from the new soup treatment, daily one agent, water, 400 ml, 200 ml warm clothing on an empty stomach in the morning and night;More than control group in Pan Li ketone, 10 mg each time, 3 times a day, 15 to 30 minutes before meals.All patients stop using other drugs during treatment period of treatment, a total of 4 weeks.This research adopts the questionnaire on the patient’s symptoms score, with symptoms integral evaluation of curative effect.Results:After statistics analysis, two groups of patients before treatment compared each individual symptom scores had no significant difference(P>0.05), so the comparable.4 weeks after treatment, two groups of patients with clinical symptoms were significantly improved, and does not appear any adverse reactions, all of the patients in the specified in the relevant auxiliary examination are required to do before and after the treatment in the normal range, no obvious abnormalities.4 weeks after treatment, the treatment group and 27 cases, clinical recovery in 11 cases, 12 cases were markedly effective, effective in 2 cases, ineffective in 2 cases, markedly effective rate was 85.19%, total effective rate was 92.59%;28 cases in the control group, the clinical recovery in 7 cases, 8 cases had marked effect, 10 cases were effective, 3 had no effect, the markedly effective rate was 53.57%, total effective rate was 89.28%.The two groups after treatment efficacy level and markedly effective rate comparison, the difference was statistically significant(P< 0.05), the total effective rate between groups, there was no statistically significant difference(P> 0.05).Treatment group and control group after dosing symptoms before the drug to the total score were significantly lower, which can show the treatment group and control group after delivery was significantly alleviate the.Symptoms of two groups after treatment, compared to the total integral difference was statistically significant(P< 0.05), treatment group and control group in improving clinical symptoms always better than the control group.After statistics analysis, two groups of subjects in each individual symptom scores compared with before treatment had no significant difference(P>0.05), comparable;Rule 4 weeks after treatment compared two groups of individual symptoms, since the proposed new soup treatment group in improving the diagnosis elimination the new full, noisy pantothenic acid, the diagnosis is afraid of cold, eat less, stay, body tired weakness, defecate, belching not great than Pan Li ketone in the control group, the difference was statistically significant(P < 0.05).Conclusion: Since the proposed new elimination decoction has good effect for functional dyspepsia, clinical is worth popularizing to use.