Advances Of Pain In Parkinson’ S Disease

Parkinson’s disease (PD) is a common neurodegenerative disease presenting with motor and non-motor symptoms in the elderly. Approximately 30-50% of the patients experience of pain in PD and it is recognized as a major cause of reduced health-related of life. Pain is one of the non-motor symptoms most frequency experienced by patients. The pathogensis underlying pain in PD is not clear and it is currently considered that pain is closely related to several factors. The risk factors for pain in PD include:age, gender, and duration of the disease. Pain in PD may be categoried into a number of different aubtypes. Increased understanding of basal ganglia pathways has provided further insights into the pathogensis of pain in PD, but the exact mechanism of pain remains unclear. This paper reviews the possible pathogenesis, risk factoes and classification for pain in PD.