A Study On The Related Factors And Clinical Characteristics Of Cirrhosis Comlicated With Gallbladder Stone

Objective:We retrospectively studied one hundred and five cirrhosis inpatients, to evaluate the prevalence of gallstones and risk factors in a large series of patients with cirrhosis.METHODS: Retrospective analysis in January 2009 to October 2013, the First Affiliated Hospital of Shihezi University clinical data 492 patients with liver cirrhosis admitted in internal in internal medicine, with 105 cases patients with hepatic cirrhosis with gallbladder stones as the observation group, liver cirrhosis patients without gallbladder stone387 cases as control group.And set up the normal control grop of 412 cases parallel abdominal B to exceed our health inspectors for the same period as the normal control group.Analysis and comparison between the three groups each group patients for age,gender,cause and Child-Pugh,grading,cirrhosis,portoal vein diameter,plasma albumin levels,platelet,total bilirubin,direct bilirubin,indirect bilrubin,apolipoprotein A and triglycerides,high-density lipoprotein cholesterol(hdl-c),total bile acid index differences,such as from the above aspects to explore the hepatic cirrhosis with gallbladder calculi occur factors and clinical characteristics of the merger compared to patients with gallbladder stone for the prevention of liver cirrhosis combined gallstones and provide a basis for clinical treatment.RESULTS: In this group the incidence of cirrhosis of gallstones was 21.3%(105/492),significantly higher than the general population incidence of simple gallstones5.6%(23/412,p=0.000<0.05),Men and women in the incidence of liver cirrhosis patients with gallbladder stone obvious difference(P > 0.05).The age of patients with cirrhosis complicated with gallbladder stones is high.Cirrhosis combined incidence of gallstone disease associated with liver function Child- Pugh grading(P < 0.05), and with the reduce the incidence of progressive increase of liver function.To different causes in patients with cirrhosis of the liver,hepatitis b after merger gall bladder calculi incidence was significantly higher in patients with cirrhosis liver cirrhosis after hepatitis c, alcoholic liver cirrhosis and other types of liver cirrhosis(P < 0.05).Liver cirrhosis portal vein diameter 1.3cm in 165 cases,a total of 32 cases of gallbladder stones were common(30.48%).The portal vein diameter less than 1.3cm higer than those.Univariate analysis showed that patients with hepatocirrhosis with gallstones in portal vein diameter, direct bilirubin, apolipoprotein A and high-density lipoprotein cholesterol(hdl-c), triglycerides compared between difference had statistical significance(P <0.05), while in,total bile acid is no significant statistical differences between description bilirubin(P > 0.05).CONCLUSION:1. In patients with cirrhosis combined gallstones.2.In patients with hepatitis B cirrhosis complicated with gallstones easily.3.The related factors of liver function Child-Pugh grade,total bilirubin,direct bilirubin,indirect bilirubin,apolipoprotein A,high density lipoprotein,triglyceride for liver cirrhosis and gallbladder stone.