Study On Sleep Disorder And Relevant Factors In Adults With Epilepsy

Objective:To probe into sleep disorders and risk factors of adults with epilepsy. Methods:102 adult outpatients with epilepsy who had visited the neurological clinic of the First Hospital of Shanxi Medical University from Dec. 2013 to Dec. 2014 were included. 46 Control participants were recruited, who could be age and gender matched with epileptic patients. The epileptic patients were divided into epilepsy combined with sleep disorders(n=40) and epilepsy without sleep disorders(n=62). We used general condition questionnaire, PSQI, SAS and SDS in this study. We analyzed the data with SAS9.2 statistical analysis software.Quantitative datas such as age,episode age,course of disease,anxiety and depression were analyzed by T-test and non-parametric test. Quantitative datas such as gender,marital status,profession station,the number of AEDs and seizure type were analyzed by chi-square test. Multiple factors analysis were adopt logistic regression. Results:(1)Sleep disorders in epileptic patients was obviously higher than controls(39.22% vs 21.74%,P<0.05);(2)In epilepsy group, the univariate analysis showed that there was correlation between sleep disorders with age(t=-2.80,P=0.0061), episode age(t=2.037,P=0.0417), anxiety(t=-5.93,P < 0.001) and depression(t=-5.71,P < 0.001), marital status(2c=3.9883,P=0.0458),the number of AEDs(2c=1.7893,P=0.0497), seizure frequency(2c=4,1839,P < 0.001), seizure type(2c=12.1538,P=0.0005);(3)Logistic regression analysis showed that generalized seizure, seizure not controlled,anxiety and depression were obviously related to sleep disorders in epilepsy patients(P<0.05). Conclusions:Epilepsy patients were more likely to have sleep disorders than general people.Generalized seizure, seizure not controlled,anxiety and depression were risk factors of epilepsy patients with sleep disorders.