Study On Effect Of Standardized Integrated Diabetes Control Intervention On Therapeutic Regimen For Type-2 Diabetic Patients In Communities From Shihezi City

Objective: To understand the baseline situation of blood glucose control and anti-diabetic therapeutic regimen of type-2 diabetic patients in Shehezi City community, to observe the improvements in glucose-target-rate, medication compliance, adverse drug reaction, and reasonable drug use rate and relevant influencing factors among type-2 diabetic patients undergoing standardized integrated control intervention, and to provide evidences for promoting and implementing a systematic, standard, integrated diabetes control system regimen in the Xinjiang Corps. Methods: A total of 312 type-2 diabetic patients were randomly selected from 13 communities within the jurisdiction of Shihezi City and divided into normal group and strengthened group: the strengthened group received one follow-up visit every three months, while the normal group received one follow-up visit every six months during a 12-month obvervation. Questionnaire surveys were carried out and serum biochemical indexes were collected after each baseline investigation and follow-up visit. Results: In the anti-diabetic therapeutic regimen, single-drug comprised 70.83%, two-drug 23.08%, three-drug or above 0.32%, and lifestyle intervention 5.77% during the baseline investigations; the glucose-target-rate was 11.54%; patients with poor medicine compliance comprised 38.14%, patients with adverse reactions 19.87%, and patients receiving irrational therapeutic regimen 89.74%. The hemoglobin A1 C achieved rates and medicine compliance and reasonability in both groups after integrated control were much better than those before the integrated control(P<0.05), and those in the strengthened group were better than those in the normal group(P<0.05). The adverse reactions in the strengthened group were much lowered than those before the integrated control(P<0.05), but those in the normal group had no statistically significant changes. A multivariate regression analysis showed that the intervention effect of integrated control on therapeutic regimen was correlated with academic background, economic income and frequency of follow-up visit of the patients. Conclusion: The blood glucose control and rational drug use among type-2 diabetic patients in 13 communities in Shihezi City are low, but integrated control prevention can provide relevant improvements. Moreover, well-educated patients with high incomes and high frequencies of follow-up visits receive more rational therapeutic regimen after integrated control.