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Exploration And The Clinical Significance Of Parathyroid Index In Operation

Posted on:2016-09-18Degree:MasterType:Thesis
Country:ChinaCandidate:Q B LinFull Text:PDF
GTID:2284330479495785Subject:Surgery
Abstract/Summary:PDF Full Text Request
Objective Raise parathyroid scoring index in the operation, verify relationship of parathyroid index and postoperative parathyroid function preliminarily.Evaluate the function of the parathyroid gland in thyroid surgery by this system.Methods Raise the parathyroid index in suit and the parathyroid transplantation index.In the same surgical team, thyroid tumors confirmed by pathology in 137 cases between July 2014 and December 2014 were studied.There are 22 male patients(16.06%) and 115 female patients(83.94%).the age of patients is between 18 ~ 73, the average age is(44.67 士 12.42). Monitoring the preoperative serum parathyroid hormone,calcium and postoperative 12-24 hours of parathyroid hormone,calcium, serum parathyroid hormone and calcium after two weeks. According to the 2 weeks after operation, serum parathyroid hormone(PTH2) in the preoperative serum parathyroid hormone(PTH0) ratio,we assess the damage of parathyroid function. According to the parathyroid index, we obtain index difference after operation treatment finally.Using SPSS 19.0 statistical software for data analysis, count data useχ2 test, measurement data use t test, P < 0.05 for the standard with statistical difference. The ratio of postoperative serum parathyroid hormone and serum parathyroid hormone after two weeks(PTH2/PTH0) is for the Y axis, and the difference of parathyroid index is for X axis.Describe a scatter diagram.Both of them are analysed by the SPSS19.0 statistical software, results suggest that relevance, which P < 0.05. Use receiver operator characteristic curve(ROC) process. The difference of parathyroid index is for the test variables.The result of hypoparathyroidism which is defined by serum parathyroid hormone after two weeks is state variables for the analysis of ROC curve, P < 0.05 for the standard with statistical difference.Results 1.After two weeks serum PTH, serum calcium and preoperative serum PTH, serum calcium is analyzed by paired t test, there is statistical significance(P < 0.05).2. The ratio of postoperative serum parathyroid hormone in two weeks and the serum parathyroid hormone before operation(PTH2/PTH0) and parathyroid index difference of the linear regression analysis, results suggest that relevance, which R=0.29, P=0.001.3.The area under the ROC curve was 0.68. When the score is 8.75 points, the sensitivity was 0.81, specificity was 0.57.Conclusion 1. Thyroid operation is bound to have an impact on parathyroid function.2. The intraoperative parathyroid index has statistical significance after the statistical analysis. Prediction of parathyroid function after surgery has diagnostic value.
Keywords/Search Tags:Thyroidectomy, Parathyroid glands, Hypoparathyroidism, Parathyroid index
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