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MSCT Diagnostic Value Of Benign Or Malignant Thyroid Focal Lesions And Its Comparative Study With Ultrasound

Posted on:2016-05-31Degree:MasterType:Thesis
Country:ChinaCandidate:T J ZhangFull Text:PDF
GTID:2284330479492320Subject:Imaging and nuclear medicine
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Objective:(1)conclude diffrtent MSCT figures of benign and malignant thyroid focal lesions.(2)MSCT diagnostic value of benign and malignant thyroid focal lesions.(3)compare diagonostic value between MSCT and ultrasound. Methods:(1)collect patients met in criteria with focal lesions in thyroid to check MSCT scan and conteast-enhanced scan, read by 2 or more team experts(D.B.T),and diagnosis the nature of lesions, and conclude figures.(2)same patients check the ultrasound,read by 2 or more experts(D.B.T),collect and conclude figures.(3)all cases underwent surgery hisology or biopsy examination, than get the result(golden standard), devide all cases into two groups(group A and group B) by the golden standard, compare the MSCT and ultrasound results with golden standard, conclude diagnostic value of MSCT for nature of thyroid nodules after statistical analysis. compare the values with ultrasound result,get the conclusion. Results:(1)investigates a total of 60 patients with thyroid focal lesions aged distribution between 22-64 years old, the average age is(46.86±5.62)years old. the sex ratio is 42/18,single nodule in left leaf have 25 cases, single nodule in right leaf have 20 cases, single nodule in isthmus have 7 cases, multi-nodules in thyroid gland have 8 cases,benign nodules have 31 cases, malignant nodules have 29 cases.(2)display rate of thyroid nodules is 91.67% in CT,95% in ultrasound. the mean value of three line in benign nodule is long(15.86±5.76)mm, wide(11.71±5.65)mm, high(12.32±6.39)mm; the mean value of three line in malignant is long(15.47±5.83)mm, wide(11.58±5.62)mm, high(12.38±6.71)mm.the size of two groups of nodules has no statistical significance; The calcification incidence of MSCT in malignant thyroid nodule was 82.67%, benign is 80.65%.The calcification incidence between two groups has no obvious statistical significance. The incidence of sand calcification in malignant nodules was 38.71%,. The incidence of sand calcification in benign nodules was 10.35%,the incidence of two groups has statistical significance, sand calcification are more likely to appear in malignant nodules. the display rate of calcification in MSCT is 100%,and 91.84% in ultrasound, the results has statistical significance.it shows MSCT is more easy to find nodular calcification; cervical lymph node enlargement in benign nodule have 7 cases. the incidence is 22.58%, cervical lymph node enlargement in malignant nodule have 15 cases, the incidence is 51.72%,the incidence of two groups has statistical significance, the malignant nodule group is more easy to find lymph node enlargement. calcification and cystic of lymph node appear in malignant group only; the artery of thyroid gland is not enlargement in benign nodules, there are 10 cases,enlarge artery in malignant group,2 cases appear emboli among them(3) The sensitivity benign and malignant nodules in MSCT is 86.30%,specificity is 90.63%. Conclusion:(1) MSCT has high sensitivity to the calcification in thyroid nodules. Whether with the neck lymph node enlargement or not, in order to further determine the benign and malignant nodules.(2)Thyroid nodule internal sand calcification, lymph node cystic and calcification, bone metastases and vessels invaded is important value in differential diagnosis of MSCT.(3)There is no obvious difference of display rate of benign and malignant nodules in MSCT and Ultrasonic, MSCT has unique advantage in lymph and bone metastasis.
Keywords/Search Tags:thyroid, focal lesion, MSCT, ultrasound, comparative study
PDF Full Text Request
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